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Leandri M, Saturno M, Cilli M, et al. Compound action potential of sensory tail nerves in the rat. Exp Neurol. 2006;203(1):148-57doi: 10.1016/j.expneurol.2006.08.001.
Leandri, M., Saturno, M., Cilli, M., Bisaglia, M., & Lunardi, G. (2007). Compound action potential of sensory tail nerves in the rat. Experimental neurology, 203(1), 148-57. https://doi.org/10.1016/j.expneurol.2006.08.001
Leandri, Massimo, et al. "Compound action potential of sensory tail nerves in the rat." Experimental neurology vol. 203,1 (2007): 148-57. doi: https://doi.org/10.1016/j.expneurol.2006.08.001
Leandri M, Saturno M, Cilli M, Bisaglia M, Lunardi G. Compound action potential of sensory tail nerves in the rat. Exp Neurol. 2007 Jan;203(1):148-57. doi: 10.1016/j.expneurol.2006.08.001. Epub 2006 Sep 07. PMID: 16962099.
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Exp Neurol. 2007 Jan;203(1):148-57. doi: 10.1016/j.expneurol.2006.08.001. Epub 2006 Sep 07.

Compound action potential of sensory tail nerves in the rat.

Experimental neurology

Massimo Leandri, Moreno Saturno, Michele Cilli, Michela Bisaglia, Gianluigi Lunardi

Affiliations

  1. Interuniversity Centre for Pain Neurophysiology, University of Genova, Italy. [email protected]

PMID: 16962099 DOI: 10.1016/j.expneurol.2006.08.001

Abstract

Assessment of the conduction velocity of motor fibers of the rat tail nerves has been used by some authors in the past, but very little is known about the sensory fibers. In 10 adult rats, weighing between 320 and 380 g, responses from the nerves and muscles of the tail have been recorded after stimulation at its root and tip. It was found that stimulation of the tip involved mainly sensory fibers, of which two main groups could be identified. One faster group, conducting within the range of 38-27 m/s, and one slower group with range 14-7 m/s. The bipolar recording configuration was found to be optimal for sensory recording. Stimulation of the tail root evoked a motor response, which was preceded by a very small neurographic activity, due to the fastest sensory fibers conducting antidromically. The conduction velocity of motor fibers was calculated to be approximately 19 m/s. Distance traveled by the volley can be assessed with excellent precision on the tail nerves; hence the calculated conduction velocities are highly reliable and reproducible. We propose that the tail nerves may be a useful tool for evaluation of conduction velocity of Abeta and Adelta afferents. As the technique is just minimally invasive, the test can be repeated a number of times in animals under chronic experimental conditions.

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