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Gan To Kagaku Ryoho. 1992 Jan;19(1):107-10.

[Successful treatment of disseminated breast cancer with combination therapy of 5'-deoxy-5'-fluorouridine (5'-DFUR), medroxyprogesterone acetate (MPA) and cyclophosphamide (CPA)].

Gan to kagaku ryoho. Cancer & chemotherapy

[Article in Japanese]
Y Takatsuka, T Katoh, I Tsumura, K Kobayakawa, T Kawahara

Affiliations

  1. Dept. of Surgery, Osaka National Hospital, Japan.

PMID: 1530905

Abstract

A 54 year-old female patient with disseminated breast cancer refractory to various kinds of previous therapies was treated with a combination therapy of 5'-DFUR, MPA and CPA. Partial response (PR) was obtained both against pleural and liver metastases with complete disappearance (CR) of soft tissue lesions and was still being continued for the following 7 months. No serious side effects were observed except for a mild degree of diarrhea and moon face. The patient was enjoying a favorable quality of life. We confirmed that this combination regimen was effective as the second line treatment for disseminated breast cancer.

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