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Ipsen T, Jørgensen PS, Damholt V, et al. Gentamicin-collagen sponge for local applications. 10 cases of chronic osteomyelitis followed for 1 year. Acta Orthop Scand. 1991;62(6):592-4doi: 10.3109/17453679108994503.
Ipsen, T., Jørgensen, P. S., Damholt, V., & Tørholm, C. (1991). Gentamicin-collagen sponge for local applications. 10 cases of chronic osteomyelitis followed for 1 year. Acta orthopaedica Scandinavica, 62(6), 592-4. https://doi.org/10.3109/17453679108994503
Ipsen, T, et al. "Gentamicin-collagen sponge for local applications. 10 cases of chronic osteomyelitis followed for 1 year." Acta orthopaedica Scandinavica vol. 62,6 (1991): 592-4. doi: https://doi.org/10.3109/17453679108994503
Ipsen T, Jørgensen PS, Damholt V, Tørholm C. Gentamicin-collagen sponge for local applications. 10 cases of chronic osteomyelitis followed for 1 year. Acta Orthop Scand. 1991 Dec;62(6):592-4. doi: 10.3109/17453679108994503. PMID: 1767654.
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Acta Orthop Scand. 1991 Dec;62(6):592-4. doi: 10.3109/17453679108994503.

Gentamicin-collagen sponge for local applications. 10 cases of chronic osteomyelitis followed for 1 year.

Acta orthopaedica Scandinavica

T Ipsen, P S Jørgensen, V Damholt, C Tørholm

Affiliations

  1. University Department of Orthopedics, Odense, Denmark.

PMID: 1767654 DOI: 10.3109/17453679108994503

Abstract

A bovine collagen sponge containing gentamicin was applied locally in 10 patients with chronic osteomyelitis who were then followed for 1 year postoperatively. No adverse effects or recurrence of infections was observed. The release of gentamicin from the sponge was more complete and rapid than has been reported with polymethyl methacrylate (PMMA) beads. Compared with previous reports on PMMA beads, a much higher gentamicin concentration in the wound exudate can be expected after implantation of the collagen sponge, which is easy to apply and does not require a second operation for removal.

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