Transfus Apher Sci. 2004 Aug;31(1):67-73. doi: 10.1016/j.transci.2004.04.002.
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis
Jerard Seghatchian
PMID: 15294197 DOI: 10.1016/j.transci.2004.04.002
The main objective of this overview is to highlight the impact of new developments in the processing of plasma, on the quality, safety and efficacy fresh frozen plasma (FFP). Based on the currently available information, it is suggested that current guidelines need an urgent review to include more relevant criteria of acceptability for therapeutic plasma. Moreover additional streamlining of FFP production, using selective donor panel, will improve the uniformity of therapeutic plasma and lower the potential risks of transfusion reactions.