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Brumfitt W, Hamilton-Miller JM. In-vitro activity of daptomycin against a worldwide collection of methicillin-resistant Staphylococcus aureus. Drugs Exp Clin Res. 1992;18(9):367-9
Brumfitt, W., & Hamilton-Miller, J. M. (1992). In-vitro activity of daptomycin against a worldwide collection of methicillin-resistant Staphylococcus aureus. Drugs under experimental and clinical research, 18(9), 367-9.
Brumfitt, W, and Hamilton-Miller, J M. "In-vitro activity of daptomycin against a worldwide collection of methicillin-resistant Staphylococcus aureus." Drugs under experimental and clinical research vol. 18,9 (1992): 367-9.
Brumfitt W, Hamilton-Miller JM. In-vitro activity of daptomycin against a worldwide collection of methicillin-resistant Staphylococcus aureus. Drugs Exp Clin Res. 1992;18(9):367-9. PMID: 1338590.
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Drugs Exp Clin Res. 1992;18(9):367-9.

In-vitro activity of daptomycin against a worldwide collection of methicillin-resistant Staphylococcus aureus.

Drugs under experimental and clinical research

W Brumfitt, J M Hamilton-Miller

Affiliations

  1. Department of Medical Microbiology, Royal Free Hospital School of Medicine, London, UK.

PMID: 1338590

Abstract

Minimum inhibitory and minimum bactericidal concentrations (MIC and MBC) of daptomycin and of vancomycin have been compared against 80 strains of methicillin-resistant Staphylococcus aureus isolated from many parts of the world. In the presence of 30 mg/l of Ca++, daptomycin at 4 mg/l killed all the strains tested, and was only slightly less active than vancomycin.

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