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Hosp Pract (Off Ed). 1992 Oct 15;27(10):189-94, 196, 199 passim. doi: 10.1080/21548331.1992.11705515.

Left ventricular hypertrophy and diastolic dysfunction.

Hospital practice (Office ed.)

B H Lorell

Affiliations

  1. Harvard Medical School, Boston.

PMID: 1400669 DOI: 10.1080/21548331.1992.11705515

Abstract

The hypertrophied heart generally preserves systolic function, but it pays a price in diastolic dysfunction. Coronary reserve is impaired and susceptibility to myocardial ischemia increased. The pathophysiology is managed by addressing causes of pressure overload, preventing tachycardia, or, of course, by specific strategies to reduce or eliminate ischemia.

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