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Upton CJ, Milner AD, Stokes GM. Episodic bradycardia in preterm infants. Arch Dis Child. 1992;67(7):831-4doi: 10.1136/adc.67.7_spec_no.831.
Upton, C. J., Milner, A. D., & Stokes, G. M. (1992). Episodic bradycardia in preterm infants. Archives of disease in childhood, 67(7), 831-4. https://doi.org/10.1136/adc.67.7_spec_no.831
Upton, C J, et al. "Episodic bradycardia in preterm infants." Archives of disease in childhood vol. 67,7 (1992): 831-4. doi: https://doi.org/10.1136/adc.67.7_spec_no.831
Upton CJ, Milner AD, Stokes GM. Episodic bradycardia in preterm infants. Arch Dis Child. 1992 Jul;67(7):831-4. doi: 10.1136/adc.67.7_spec_no.831. PMID: 1519984; PMCID: PMC1590410.
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Arch Dis Child. 1992 Jul;67(7):831-4. doi: 10.1136/adc.67.7_spec_no.831.

Episodic bradycardia in preterm infants.

Archives of disease in childhood

C J Upton, A D Milner, G M Stokes

Affiliations

  1. Department of Neonatal Medicine and Surgery, City Hospital, Nottingham.

PMID: 1519984 PMCID: PMC1590410 DOI: 10.1136/adc.67.7_spec_no.831
Free PMC Article

Abstract

To analyse factors likely to precipitate bradycardia, 27 preterm infants born at 32 weeks' gestation or less were studied on 89 occasions. Polygraphic recordings of electrocardiography, oxygen saturation, and respiratory effort were made. Subsequently, upper airway flow was measured by a mask and pressure transducer. In 605 episodes detected during initial recordings, time of onset of bradycardia correlated positively with apnoea duration, with bradycardia often occurring as respiratory effort resumed. Airway closure occurred in 88% of apnoeas associated with bradycardia during flow measurements, and was significantly more common than in apnoea without bradycardia (64%). We suggest that bradycardia is most commonly a reflex response to the resumption of respiratory effort against a closed upper airway as apnoea is terminated, and that this reflex is potentiated by hypoxaemia.

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