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Qui BS, Cho CH, Ogle CW. A correlative study on serum cholylglycine levels in hepatobiliary disease. Horm Metab Res. 1992;24(9):443-5doi: 10.1055/s-2007-1003355.
Qui, B. S., Cho, C. H., & Ogle, C. W. (1992). A correlative study on serum cholylglycine levels in hepatobiliary disease. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 24(9), 443-5. https://doi.org/10.1055/s-2007-1003355
Qui, B S, et al. "A correlative study on serum cholylglycine levels in hepatobiliary disease." Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme vol. 24,9 (1992): 443-5. doi: https://doi.org/10.1055/s-2007-1003355
Qui BS, Cho CH, Ogle CW. A correlative study on serum cholylglycine levels in hepatobiliary disease. Horm Metab Res. 1992 Sep;24(9):443-5. doi: 10.1055/s-2007-1003355. PMID: 1427617.
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Georg Thieme Verlag Stuttgart, New York

Horm Metab Res. 1992 Sep;24(9):443-5. doi: 10.1055/s-2007-1003355.

A correlative study on serum cholylglycine levels in hepatobiliary disease.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme

B S Qui, C H Cho, C W Ogle

Affiliations

  1. Department of Internal Medicine, First Affiliated Hospital of the Shantou University Medical College, P. R. China.

PMID: 1427617 DOI: 10.1055/s-2007-1003355

Abstract

The serum cholylglycine (CG), alanine aminotransferase (ALT) and total bilirubin levels were studied in 210 patients with hepatobiliary disease and in 70 healthy subjects. Serum CG concentrations in all the hepatobiliary diseases were found to be significantly higher than those of their controls. Patients with abnormal increases in ALT and bilirubin levels also showed raised CG concentrations; however, some patients with normal ALT and bilirubin levels, still had markedly elevated CG values. Patients with hepatic cirrhosis had high serum CG levels, followed, in descending order, by chronic active hepatitis and chronic persistent hepatitis. In the cholecystitis and cholelithiasis cases, their CG levels were significantly higher than those of the controls but lower than the values in hepatic disease patients; however, more cholecystitis cases had abnormally high serum bilirubin levels than CG. The results also show that serum CG concentrations vary in the different hepatobiliary diseases, and that serial CG measurements are more sensitive than measuring ALT and bilirubin levels in the diagnosis of hepatic diseases. Serum CG can be used as an index for evaluating the activity of chronic hepatitis; it can also be employed as a diagnostic tool in cholecystitis and cholelithiasis.

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