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Brouwer OF, Laboyrie PM, Peters AC, et al. Follow-up magnetic resonance imaging in Hallervorden-Spatz disease. Clin Neurol Neurosurg. 1992;94:S57-60doi: 10.1016/0303-8467(92)90023-v.
Brouwer, O. F., Laboyrie, P. M., Peters, A. C., & Vielvoye, G. J. (1992). Follow-up magnetic resonance imaging in Hallervorden-Spatz disease. Clinical neurology and neurosurgery, 94S57-60. https://doi.org/10.1016/0303-8467(92)90023-v
Brouwer, O F, et al. "Follow-up magnetic resonance imaging in Hallervorden-Spatz disease." Clinical neurology and neurosurgery vol. 94 (1992): S57-60. doi: https://doi.org/10.1016/0303-8467(92)90023-v
Brouwer OF, Laboyrie PM, Peters AC, Vielvoye GJ. Follow-up magnetic resonance imaging in Hallervorden-Spatz disease. Clin Neurol Neurosurg. 1992;94:S57-60. doi: 10.1016/0303-8467(92)90023-v. PMID: 1320520.
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Clin Neurol Neurosurg. 1992;94:S57-60. doi: 10.1016/0303-8467(92)90023-v.

Follow-up magnetic resonance imaging in Hallervorden-Spatz disease.

Clinical neurology and neurosurgery

O F Brouwer, P M Laboyrie, A C Peters, G J Vielvoye

Affiliations

  1. Department of Neurology, University Hospital, Leiden, The Netherlands.

PMID: 1320520 DOI: 10.1016/0303-8467(92)90023-v

Abstract

Bilateral high signal emitting areas in the globus pallidus surrounded by low signal emitting areas have been described as a typical MRI finding in Hallervorden-Spatz disease (HSD). We made a diagnosis of HSD in an 11-year-old girl with progressive dystonia of 4 years duration who showed these typical MRI abnormalities. An initial MRI at the age of 9 was normal. Pathological confirmation of these typical MRI findings has not yet been described, but earlier reports as well as our case suggest that MRI may be helpful in making a clinical diagnosis of HSD. This case further shows that MRI may be normal in an early stage of the disease.

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