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Eur J Clin Microbiol Infect Dis. 1992 Aug;11(8):732-7. doi: 10.1007/BF01989980.

Effect of subinhibitory concentrations of cefamandole and cefuroxime on adherence of Staphylococcus aureus and Staphylococcus epidermidis to polystyrene culture plates.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology

H Carsenti-Etesse, J Durant, E Bernard, V Mondain, J Entenza, P Dellamonica

Affiliations

  1. Department of Infectious Diseases, Archet Hospital, Nice, France.

PMID: 1425733 DOI: 10.1007/BF01989980

Abstract

The ability of cefamandole and cefuroxime to inhibit adherence of staphylococci to polystyrene culture plates was tested in an in vitro assay using eight strains each of Staphylococcus aureus and Staphylococcus epidermidis. The results indicated that subinhibitory concentrations of cefamandole and cefuroxime altered the adherence ability of both staphylococcal species, inhibition of adherence being more marked in the presence of cefamandole. It may be important to consider antiadherence properties in association with bactericidal activity when selecting agents for antibiotic prophylaxis.

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