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Lanitz EC, Gonska BD, Schrader J. Blutdruckvariabilität und transiente Myokardischämien bei Patienten mit Essentieller Hypertonie. [Blood pressure variability and transient myocardial ischemia in patients with essential hypertension]. Z Kardiol. 1992;81:37-9
Lanitz, E. C., Gonska, B. D., & Schrader, J. (1992). Blutdruckvariabilität und transiente Myokardischämien bei Patienten mit Essentieller Hypertonie. [Blood pressure variability and transient myocardial ischemia in patients with essential hypertension]. Zeitschrift fur Kardiologie, 8137-9.
Lanitz, E C, et al. "Blutdruckvariabilität und transiente Myokardischämien bei Patienten mit Essentieller Hypertonie." [Blood pressure variability and transient myocardial ischemia in patients with essential hypertension]. Zeitschrift fur Kardiologie vol. 81 (1992): 37-9.
Lanitz EC, Gonska BD, Schrader J. Blutdruckvariabilität und transiente Myokardischämien bei Patienten mit Essentieller Hypertonie. [Blood pressure variability and transient myocardial ischemia in patients with essential hypertension]. Z Kardiol. 1992;81:37-9. German. PMID: 1514310.
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Z Kardiol. 1992;81:37-9.

[Blood pressure variability and transient myocardial ischemia in patients with essential hypertension].

Zeitschrift fur Kardiologie

[Article in German]
E C Lanitz, B D Gonska, J Schrader

Affiliations

  1. Abt. für Kardiologie und Pulmonologie, Medizinische Universitätsklinik Göttingen.

PMID: 1514310

Abstract

To determine whether myocardial ischemia is accompanied by variation in heart rate and/or blood pressure, ST-segment analysis on Holter-ECG and ambulatory blood pressure monitoring was performed in 78 patients (64 males/14 females) with essential hypertension. Thirteen out of 55 patients (24%) with angiographically proven coronary artery disease (CAD) showed ST-segment depression (ST-D; group A pos). We observed 41 ST-D (1-11 ST-D; median: 2) lasting from 1 min to 70 min 15 s (median: 4 min 42 s) and an average depression of 185 +/- 48 mV. In comparison, in 6 of 23 patients (26%) with a normal angiogram 24 ST-D (1-10; median: 3; group B pos), which showed longer duration (1 min to 109 min 20 s; median: 11 min 10 s) and less depression (137 +/- 47 mV) have been found. 73.3% of all ST-D in group A pos and all in group B pos were preceded by an average increase in heart rate of 13 bpm. Exclusively, 12 episodes of ischemia (29.3%) in patients with CAD and 8 (33.3%) in patients without CAD were accompanied by an increase in blood pressure, which was more distinct in group A pos. Transient myocardial ischemia can be shown in hypertensive heart disease unrelated to CAD. A clear correlation between an increase in blood pressure and ST-D could not be proven.

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