J Theor Biol. 1992 Sep 21;158(2):231-43. doi: 10.1016/s0022-5193(05)80721-0.

The chirality of ground DNA knots and links.

Journal of theoretical biology

C Liang, Y Jiang

PMID: 1474845 DOI: 10.1016/s0022-5193(05)80721-0

Abstract

The chirality of ground DNA knots and links is described and characterized in terms of color symmetry groups (CSG), i.e. color symmetry groups I and II, which correspond to topochirality (topological chirality) and topoachirality (topological achirality) which bear an uncanny resemblance to point groups I (proper) and point groups II (improper) used for testing geochirality (geometrical chirality) and geoachirality (geometrical achirality), respectively. By regarding these two crossing modes in mirror images as white and black vertices, DNA knots and links with minimal crossings can be mapped to vertex-bicolored graphs under a working hypothesis that DNA knots and links exist in ground states with minimal energy m0. The color symmetry group of a vertex-bicolored graph G is defined as the set of all permutations and permutation asymmetrizations of the vertices of G that preserve its topology (connectivity), where asymmetrization, denoted as (a), is the operation of changing vertices' colors, and a permutation followed by an (a) is a permutation asymmetrization. The color symmetry groups I contains only permutations, whereas color symmetry groups II comprise permutation asymmetrizations as well as permutations. Four DNA knots and links in nature are analyzed and tabulated consisely. In addition, the well-known figure-of-eight knot and Borromean rings are discussed in much the same way.

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Substances

• Macromolecular Substances
• DNA

MeSH terms

• DNA / chemistry
• Macromolecular Substances
• Models, Chemical*

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• Journal Article

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