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Atypon Free PMC Article

Antimicrob Agents Chemother. 1976 Feb;9(2):288-91. doi: 10.1128/AAC.9.2.288.

Antimicrobial susceptibilities of shigellae isolated in Houston, Texas, in 1974.

Antimicrobial agents and chemotherapy

P A Byers, H L Dupont, M C Goldschmidt

PMID: 1267426 PMCID: PMC429516 DOI: 10.1128/AAC.9.2.288
Free PMC Article

Abstract

One hundred seventy-three strains of shigellae (113 Shigella sonnei, 56 S. flexneri, and four others) isolated in Houston during 1974 were tested for susceptibility to commonly used and newer antimicrobial agents. Forty-five percent of S. sonnei strains were susceptible to ampicillin, whereas 93% of S. flexneri strains were susceptible to that agent. S. sonnei and S. flexneri strains were equally susceptible to tetracycline (35 and 33%, respectively). All 173 strains were uniformly susceptible to quinoline drugs (cinoxacin, oxolinic acid, and nalidixic acid) and to trimethoprim-sulfamethoxazole. This study supports recent suggestions that the initial therapy of bacillary dysentery no longer should be ampicillin or tetracycline. It remains for field testing to determine whether quinoline agents or trimethoprim-sulfamethoxazole will be the treatment of choice.

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References

  1. JAMA. 1972 Jul 3;221(1):45-7 - PubMed
  2. J Infect Dis. 1971 May;123(5):477-84 - PubMed
  3. Arch Dis Child. 1973 Apr;48(4):305-12 - PubMed
  4. Chemotherapy. 1974;20(2):113-9 - PubMed
  5. Antimicrob Agents Chemother. 1974 May;5(5):439-43 - PubMed
  6. Antimicrob Agents Chemother. 1973 Sep;4(3):201-4 - PubMed
  7. J Pediatr. 1967 Jun;70(6):970-81 - PubMed
  8. JAMA. 1975 Mar 17;231(11):1159-61 - PubMed
  9. Br Med J. 1972 Jul 1;3(5817):23-6 - PubMed
  10. JAMA. 1973 Dec 24;226(13):1525-8 - PubMed
  11. Scand J Infect Dis. 1972;4(3):231-40 - PubMed
  12. Ann Intern Med. 1969 Apr;70(4):713-21 - PubMed

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