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Rev Esp Anestesiol Reanim. 1992 Nov-Dec;39(6):379-80.

[Paradoxical reaction to midazolam after its use as a sedative in regional anesthesia].

Revista espanola de anestesiologia y reanimacion

[Article in Spanish]
A Martínez-Tellería, M E Cano, R Carlos

Affiliations

  1. Departamento de Anestesiología y Reanimación, Hospital Universitario, Granada.

PMID: 1293657

Abstract

We report 3 cases of paradoxical reaction to midazolam after being used for sedation during regional anesthesia. The picture was characterized by a marked aggressiveness. In one case the reaction was treated with general anesthesia, whereas in the other two patients the clinical picture was rapidly reversed by administration of flumazenil. We describe the possible causative mechanisms of this reaction as well as their treatment.

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