Presse Med. 1992 Nov 28;21(40):1901-4.

[Hepatobiliary manifestations in AIDS in adults. Place of cholecystectomy].

Presse medicale (Paris, France : 1983)

[Article in French]
P Wind, J P Sales, W Lowenstein, A Berger, P Frileux, P H Cugnenc

PMID: 1293600

Abstract

In AIDS patients an acalculous cholecystitis may be responsible for abdominal pain subsiding after cholecystectomy. But the indications for cholecystectomy are not clear: cholecystitis is usually associated with diffuse cholangitis and this might cause the symptoms. Since 1985, 8 AIDS patients have undergone cholecystectomy for acute cholecystitis. Ultrasonography revealed a 5 to 12 mm thickening of the gallbladder wall in all of them and gallbladder stones in two; four patients had cholangitis. The decision to operate was based on persistent pain associated with fever, poor general condition and muscular rigidity at palpation. Four patients had septic shock at the time of surgery; one died in the immediate postoperative period. In all other patients pain and septic syndrome subsided. Two patients died of AIDS complications 20 days after surgery; the remaining five died of AIDS 6, 9, 10, 12 and 14 months respectively after surgery; in two of them cholestasis had reappeared due to cholangitis. To summarize, in the 8 AIDS patients studied cholecystectomy was performed for clinical deterioration. Gallbladder pathology was responsible for the abdominal pain and the febrile general condition which was relieved by cholecystectomy.

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MeSH terms

• Acquired Immunodeficiency Syndrome / complications
• Acute Disease
• Adult
• Cholangiography
• Cholangitis / complications
• Cholecystectomy / methods
• Cholecystitis / diagnostic imaging
• Cholecystitis / etiology
• Cholecystitis / surgery
• Cholelithiasis / complications
• Female
• Humans
• Male
• Middle Aged
• Ultrasonography

Publication Types

• Journal Article

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