Display options
Cite
Nerlo H, Czarnecki W, Dul R. Effect of processing technique of different dosage forms on dissolution rate of caffeine and salicylamide. Pol J Pharmacol Pharm. 1976;28(4):361-7
Nerlo, H., Czarnecki, W., & Dul, R. (1976). Effect of processing technique of different dosage forms on dissolution rate of caffeine and salicylamide. Polish journal of pharmacology and pharmacy, 28(4), 361-7.
Nerlo, H, et al. "Effect of processing technique of different dosage forms on dissolution rate of caffeine and salicylamide." Polish journal of pharmacology and pharmacy vol. 28,4 (1976): 361-7.
Nerlo H, Czarnecki W, Dul R. Effect of processing technique of different dosage forms on dissolution rate of caffeine and salicylamide. Pol J Pharmacol Pharm. 1976 May-Jun;28(4):361-7. PMID: 981026.
Copy Download .nbib Format: NLM
Share it on

Pol J Pharmacol Pharm. 1976 May-Jun;28(4):361-7.

Effect of processing technique of different dosage forms on dissolution rate of caffeine and salicylamide.

Polish journal of pharmacology and pharmacy

H Nerlo, W Czarnecki, R Dul

PMID: 981026

Abstract

The dissolution rate of caffeine (Cf) and salicylamide (SA) from the mixtures of powders, granulate and tablets, obtained by the direct compression and wet granulation methods, has been investigated. The results presented in plots show, that the dissolution process of Cf and SA follows the first-order kinetics. The kinetic equations are used for the calculation of the dissolution rate contants (K) for the compounds of different solubility. Chromatography did not give an evidence for the formation of an adduct of Cf and SA in the granulate and tablets prepared by the wet granulation method.

Similar articles

Substances

MeSH terms

Publication Types