Br Med J. 1975 Nov 15;4(5993):378-80. doi: 10.1136/bmj.4.5993.378.

Acute cardiomyopathy with rhabdomyolysis in chronic alcoholism.

British medical journal

B I Seneviratne

PMID: 1192080 PMCID: PMC1675252 DOI: 10.1136/bmj.4.5993.378
Free PMC Article

Abstract

Of five chronic alcoholics with acute skeletal muscle necrosis (rhabdomyolysis) three developed acute heart failure with disturbances of rhythm and conduction. Symptoms came on abruptly after a period of intensified drinking. Myocardial infarction, thiamine deficiency, and cobalt intoxication were excluded. Probably the whole spectrum of muscle disease in chronic alcoholism may be commoner than has been suspected.

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Substances

• L-Lactate Dehydrogenase
• Aspartate Aminotransferases
• Alanine Transaminase
• Creatine Kinase

MeSH terms

• Adult
• Alanine Transaminase / blood
• Alcoholism / complications
• Arrhythmias, Cardiac / etiology
• Aspartate Aminotransferases / blood
• Creatine Kinase / blood
• Heart Failure / complications
• Heart Failure / etiology
• Humans
• L-Lactate Dehydrogenase / blood
• Male
• Middle Aged
• Muscular Diseases / enzymology
• Muscular Diseases / etiology
• Myoglobinuria / etiology
• Necrosis / etiology
• Smoking / complications

Publication Types

• Case Reports
• Journal Article

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