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Witteveen SA, Hemker HC, Hollaar L, et al. Quantitation of infarct size in man by means of plasma enzyme levels. Br Heart J. 1975;37(8):795-803doi: 10.1136/hrt.37.8.795.
Witteveen, S. A., Hemker, H. C., Hollaar, L., & Hermens, W. T. (1975). Quantitation of infarct size in man by means of plasma enzyme levels. British heart journal, 37(8), 795-803. https://doi.org/10.1136/hrt.37.8.795
Witteveen, S A, et al. "Quantitation of infarct size in man by means of plasma enzyme levels." British heart journal vol. 37,8 (1975): 795-803. doi: https://doi.org/10.1136/hrt.37.8.795
Witteveen SA, Hemker HC, Hollaar L, Hermens WT. Quantitation of infarct size in man by means of plasma enzyme levels. Br Heart J. 1975 Aug;37(8):795-803. doi: 10.1136/hrt.37.8.795. PMID: 1191441; PMCID: PMC482877.
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Br Heart J. 1975 Aug;37(8):795-803. doi: 10.1136/hrt.37.8.795.

Quantitation of infarct size in man by means of plasma enzyme levels.

British heart journal

S A Witteveen, H C Hemker, L Hollaar, W T Hermens

PMID: 1191441 PMCID: PMC482877 DOI: 10.1136/hrt.37.8.795
Free PMC Article

Abstract

A method is described in which the extent of myocardial infarction in man is assessed by mathematical analysis of the rise in plasma enzyme levels after infarction. Five enzymes are used in this study: lactate dehydrogenase (LDH); alpha-hydroxybutyrate dehydrogenase (alpha-HBDH); aspartate aminotransferase (GOT); creatine phosphokinase (CPK); and phosphohexoseisomerase (PHI). It is shown that a reasonable assessment of the total enzyme release, reflecting the extent of the infarcted area, can be made when a sufficient number of blood samples are taken after infarction. This could provide a method by which to judge therapeutic effects of intervention in the course of a myocardial infarction, as demonstrated in this study by the assessment of the effect of urokinase on the enzyme release after an infarct.

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References

  1. J Clin Invest. 1973 Oct;52(10):2579-90 - PubMed
  2. J Clin Invest. 1972 Oct;51(10):2717-23 - PubMed
  3. Br Heart J. 1970 Nov;32(6):728-32 - PubMed
  4. Circulation. 1971 Jan;43(1):67-82 - PubMed
  5. Am Heart J. 1957 Aug;54(2):219-24 - PubMed
  6. Lancet. 1961 Apr 1;1(7179):698-9 - PubMed
  7. J Lab Clin Med. 1967 Apr;69(4):696-705 - PubMed
  8. Am J Pathol. 1973 Mar;70(3):401-20 - PubMed
  9. Schweiz Med Wochenschr. 1973 Dec 15;103(50):1814-6 - PubMed
  10. Am J Cardiol. 1974 Jan;33(1):82-6 - PubMed
  11. Drugs. 1973;5(5):357-445 - PubMed
  12. Br Heart J. 1974 Mar;36(3):271-9 - PubMed
  13. J Clin Invest. 1971 Dec;50(12):2614-25 - PubMed
  14. Science. 1954 Sep 24;120(3117):497-9 - PubMed
  15. J Lab Clin Med. 1958 Feb;51(2):259-65 - PubMed
  16. Am J Cardiol. 1962 Oct;10:525-31 - PubMed

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