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Finsterbush A, Friedman B. Reversibility of joint changes produced by immobilization in rabbits. Clin Orthop Relat Res. 1975;(111):290-8doi: 10.1097/00003086-197509000-00038.
Finsterbush, A., & Friedman, B. (1975). Reversibility of joint changes produced by immobilization in rabbits. Clinical orthopaedics and related research, (111), 290-8. https://doi.org/10.1097/00003086-197509000-00038
Finsterbush, A, and Friedman, B. "Reversibility of joint changes produced by immobilization in rabbits." Clinical orthopaedics and related research vol. ,111 (1975): 290-8. doi: https://doi.org/10.1097/00003086-197509000-00038
Finsterbush A, Friedman B. Reversibility of joint changes produced by immobilization in rabbits. Clin Orthop Relat Res. 1975 Sep;(111):290-8. doi: 10.1097/00003086-197509000-00038. PMID: 1157424.
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Clin Orthop Relat Res. 1975 Sep;(111):290-8. doi: 10.1097/00003086-197509000-00038.

Reversibility of joint changes produced by immobilization in rabbits.

Clinical orthopaedics and related research

A Finsterbush, B Friedman

PMID: 1157424 DOI: 10.1097/00003086-197509000-00038

Abstract

Rabbits knee joints which had been immobilized for only 2 weeks regained motion during the first 2 months of remobilization. Histologically, joint tissues were normal. Only 9 of the 14 rabbits immobilized for 6 weeks regained normal or partial knee motion. Animals that regained knee motion generally did so during the first 4 months of remobilization. There are 2 types of repair of the damaged cartilage; replacement by fibrocartilage and proliferation of chondrocytes. Normal chondrocyte alignment and normal collagen fibril orientation was not restored. Repaired cartilage did not withstand normal joint stress.

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