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Nature Publishing Group Free PMC Article

Br J Cancer. 1975 Mar;31(3):317-28. doi: 10.1038/bjc.1975.66.

An assessment of the effects of hormones on short term organ cultures of human breast carcinomata.

British journal of cancer

D I Beeby, G C Easty, J C Gazet, K Grigor, A M Neville

PMID: 1156517 PMCID: PMC2009428 DOI: 10.1038/bjc.1975.66
Free PMC Article

Abstract

Twenty-eight mammary carcinomata were maintained in organ culture in the presence of various hormones. The effects of the hormones have been assessed histologically by estimation of total dehydrogenases activity of the pentose glycolytic pathway and by the incorporation of tritiated thymidine or uridine into DNA or RNA. No significant effects on tumour cell activity due to hormones have been observed.

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