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Folia Microbiol (Praha). 2000;45(6):485-90. doi: 10.1007/BF02818714.

Effects of subinhibitory concentrations of nitroxoline on the surface properties of Escherichia coli.

Folia microbiologica

H Latrache, P Bourlioux, M Karroua, H Zahir, A Hakkou

Affiliations

  1. Laboratoire de Microbiologie, Faculté de Pharmacie, Université Paris XI, 92 296 Chátenay-Malabry, France.

PMID: 11501411 DOI: 10.1007/BF02818714

Abstract

Nitroxoline (5-nitro-8-quinolinol; NIQ) at subinhibitory concentrations (sub-MIC) decreased the adherence of uropathogenic Escherichia coli to catheter surface and significantly enhanced cell surface hydrophobicity. The surface hydrophobicity increased in the presence of sub-MIC of NIQ and also in an excess of Mg2+. The effect of NIQ on the cell surface was not related to the bacteriostatic effect of this agent. The increase in nitrogen and decrease in phosphate content in the cell surface was found in the presence of NIQ. NIQ did not inhibit the expression of fimbriae.

References

  1. Annu Rev Microbiol. 1985;39:527-56 - PubMed
  2. Rev Infect Dis. 1979 Sep-Oct;1(5):838-44 - PubMed
  3. Pathol Biol (Paris). 1989 Jun;37(5 Pt 2):600-4 - PubMed
  4. Pathol Biol (Paris). 1991 May;39(5):561-4 - PubMed
  5. Folia Microbiol (Praha). 1999;44(3):267-70 - PubMed
  6. Biochem J. 1981 Apr 15;196 (1):1-10 - PubMed
  7. N Engl J Med. 1982 Sep 9;307(11):637-42 - PubMed
  8. Biochim Biophys Acta. 1980 Nov 4;602(2):269-80 - PubMed
  9. Biochim Biophys Acta. 1988 Nov 22;945(2):324-34 - PubMed
  10. Biochimie. 1988 Aug;70(8):987-1011 - PubMed
  11. Arch Oral Biol. 1989;34(11):889-94 - PubMed
  12. Chemotherapy. 1997 Nov-Dec;43(6):424-9 - PubMed
  13. Folia Microbiol (Praha). 2000;45(1):45-9 - PubMed
  14. Folia Microbiol (Praha). 1998;43(1):104-8 - PubMed
  15. J Urol. 1988 Sep;140(3):651-5 - PubMed
  16. J Antimicrob Chemother. 1993 Jan;31(1):37-45 - PubMed
  17. Can J Surg. 1985 Jan;28(1):50-1, 54 - PubMed
  18. Biochim Biophys Acta. 1973 Feb 28;297(2):193-202 - PubMed
  19. Urol Res. 1982 Feb;10(1):37-40 - PubMed
  20. J Clin Microbiol. 1987 Dec;25(12):2253-7 - PubMed
  21. Eur J Clin Microbiol Infect Dis. 1992 Aug;11(8):732-7 - PubMed
  22. N Engl J Med. 1986 May 8;314(19):1208-13 - PubMed
  23. Rev Infect Dis. 1987 May-Jun;9(3):470-87 - PubMed
  24. Microb Pathog. 1988 May;4(5):369-77 - PubMed

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