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Eur J Drug Metab Pharmacokinet. 2001 Jan-Jun;26(1):71-6. doi: 10.1007/BF03190379.

Autoradiography in brain of Macaca fascicularis monkeys after injection of acetyl-DL-leucine [2-14C] (Tanganil).

European journal of drug metabolism and pharmacokinetics

P Benard, H Cousse, T Bengone, C Germain

Affiliations

  1. Ecole Nationale Vétérinaire, Laboratoire de Radioélements et d' Etudes Métaboliques, Toulouse, France.

PMID: 11554437 DOI: 10.1007/BF03190379

Abstract

Acetyl-DL-leucine [2-14C]: Tanganil a antivertigal drug has been injected intravenously in two macaca monkeys which have been sacrificed 2 and 5 minutes later. Radioactivity distribution has been studied by autoradiography in the brain. An important uptake of radioactivity is localized in the cortical structures and in several tisses such as nuclei of the vestibular system, including the inner ear.

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