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Schweiz Med Wochenschr. 1976 Oct 02;106(40):1383.

[Cell division, cytolysis and regeneration after cyclophosphamide].

Schweizerische medizinische Wochenschrift

[Article in German]
H P Wagner, A D Chanana, H Cottier, E P Cronkite, A Gassmann, D D Joel, J A Laissue

PMID: 1006264

Abstract

Cytokinetic effects of 5 or 20 mg cyclophosphamide/kg body weight on thoracic duct lymph and blood cells of calves were analyzed. The larger dose caused a temporary cessation of lymphoid cell division, reduced the output of nondividing small lymphoid cells and impaired proliferation of neutrophil precursors. Feedback mechanisms acting on GO/G1 cells controlled the proliferation of lymphoid cells.

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