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van Rijswijk CS, Hogendoorn PC, Taminiau AH, et al. Synovial sarcoma: dynamic contrast-enhanced MR imaging features. Skeletal Radiol. 2001;30(1):25-30doi: 10.1007/s002560000295.
van Rijswijk, C. S., Hogendoorn, P. C., Taminiau, A. H., & Bloem, J. L. (2001). Synovial sarcoma: dynamic contrast-enhanced MR imaging features. Skeletal radiology, 30(1), 25-30. https://doi.org/10.1007/s002560000295
van Rijswijk, C S, et al. "Synovial sarcoma: dynamic contrast-enhanced MR imaging features." Skeletal radiology vol. 30,1 (2001): 25-30. doi: https://doi.org/10.1007/s002560000295
van Rijswijk CS, Hogendoorn PC, Taminiau AH, Bloem JL. Synovial sarcoma: dynamic contrast-enhanced MR imaging features. Skeletal Radiol. 2001 Jan;30(1):25-30. doi: 10.1007/s002560000295. PMID: 11289631.
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Skeletal Radiol. 2001 Jan;30(1):25-30. doi: 10.1007/s002560000295.

Synovial sarcoma: dynamic contrast-enhanced MR imaging features.

Skeletal radiology

C S van Rijswijk, P C Hogendoorn, A H Taminiau, J L Bloem

Affiliations

  1. Department of Radiology, Leiden University Medical Center, The Netherlands.

PMID: 11289631 DOI: 10.1007/s002560000295

Abstract

OBJECTIVE: To determine whether previously described so-called malignant dynamic contrast-enhanced magnetic resonance (MR) imaging features--early start, peripheral enhancement and early plateau or washout phase--occur consistently in synovial sarcoma.

DESIGN AND PATIENTS: Dynamic contrast-enhanced MR images of 10 patients with histologically proven synovial sarcoma were reviewed. The start, pattern and progression of tumor enhancement were assessed and correlated with histopathology.

RESULTS: In all patients, the time interval between arterial and early tumor enhancement was less than 7 s (mean 4.40 s, SD 2.09 s). Six synovial sarcomas showed enhancement with a subsequent rapidly progressive linear increase in signal intensity followed by a plateau in one lesion and washout in five. Four lesions showed a late sustained increase in enhancement after the initial rapid increase in enhancement. The pattern of initial enhancement was peripheral in only two lesions, diffuse in four and heterogeneous in four lesions.

CONCLUSIONS: Enhancement of tumor within 7 s after arterial enhancement is, of the three parameters described previously, the only sign that occurs consistently in synovial sarcoma.

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