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Childs Nerv Syst. 2001 Jan;17(1):31-6. doi: 10.1007/s003810000356.

Cerebellar gliomas in infants: specificity, pathology, and outcome.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

M Vinchon, M M Ruchoux, G Soto-Ares, R Nicolas, P Dhellemmes

Affiliations

  1. Department of Pediatric Neurosurgery, CHRU de Lille, France. [email protected]

PMID: 11219620 DOI: 10.1007/s003810000356

Abstract

Cerebellar gliomas (CGs) in children are generally associated with a favorable outcome; however, data regarding these tumors in very young children are scarce. We report on our experience with CGs in children less than 3 years old at surgery, compared with a second group older than 3 years. From 1991 to 1996, we operated on 7 children with CGs in the first group and 43 in the second. Psychomotor delay and regression were the first symptoms in 3 cases, and 3 had macrocrania. The tumor was totally removed in all cases. One child died intraoperatively of air embolism and subdural bleeding. Three had malignant tumors (grade 3 or 4). There was no operative mortality or malignancy in the second group of patients. With a mean follow-up of 33 months, all survivors in the first group are disease-free, with no or minimal symptoms, and attend normal schools. The clinical, surgical, and pathological features suggest that children under 3 years of age represent a specific subgroup of CGs.

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