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van de Walle J, Weijers MJ. Clinical evaluation of a new oral contraceptive, 'Pregnon'. Curr Med Res Opin. 1975;3(3):151-6doi: 10.1185/03007997509113663.
van de Walle, J., & Weijers, M. J. (1975). Clinical evaluation of a new oral contraceptive, 'Pregnon'. Current medical research and opinion, 3(3), 151-6. https://doi.org/10.1185/03007997509113663
van de Walle, J, and Weijers, M J. "Clinical evaluation of a new oral contraceptive, 'Pregnon'." Current medical research and opinion vol. 3,3 (1975): 151-6. doi: https://doi.org/10.1185/03007997509113663
van de Walle J, Weijers MJ. Clinical evaluation of a new oral contraceptive, 'Pregnon'. Curr Med Res Opin. 1975;3(3):151-6. doi: 10.1185/03007997509113663. PMID: 1149483.
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Curr Med Res Opin. 1975;3(3):151-6. doi: 10.1185/03007997509113663.

Clinical evaluation of a new oral contraceptive, 'Pregnon'.

Current medical research and opinion

J van de Walle, M J Weijers

PMID: 1149483 DOI: 10.1185/03007997509113663

Abstract

'Pregnon', a new oral contraceptive containing 1 mg. lynestrenol and 0.05 mg. ethinyl oestradiol, was administered cyclically to 639 women of fertile age over a total of 9,159 cycles. There were no pregnancies. In most cases the withdrawal bleeding resembled normal menstruation. The incidence of metrorrhagia was relatively low and when it did occur it was usually confined to the early treatment cycles and was of very limited duration. The objective and subjective tolerance was excellent.

Keywords: Clinical Research; Contraception; Contraceptive Agents, Estrogen--administraction and dosage; Contraceptive Agents, Estrogen--side effects; Contraceptive Agents, Female--administraction and dosage; Contraceptive Agents, Female--side effects; Contraceptive Agents, Progestin--administraction and dosage; Contraceptive Agents, Progestin--side effects; Contraceptive Agents--administraction and dosage; Contraceptive Agents--side effects; Contraceptive Effectiveness; Contraceptive Methods; Contraceptive Methods--side effects; Contraceptive Usage; Diseases; Ethinyl Estradiol--administraction and dosage; Ethinyl Estradiol--side effects; Evaluation; Family Planning; Lynestrenol--administraction and dosage; Lynestrenol--side effects; Menstruation Disorders; Method Acceptability; Oral Contraceptives, Combined; Oral Contraceptives--side effects; Research Methodology; Use-effectiveness

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