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Semin Gastrointest Dis. 2000 Jul;11(3):152-6.

Postoperative management of local colorectal cancer: therapy and surveillance.

Seminars in gastrointestinal disease

D S Weinberg, R Desnoyers, A Gelmann, B M Boman, S A Waldman

Affiliations

  1. Department of Medicine, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.

PMID: 10950462

Abstract

Adjuvant therapy is widely recommended for stage III colon cancer and stages II and III rectal cancer. Although fluorouracil-based regimens are standard, newer agents either alone or in combination may improve response rates. Although nearly all patients enter a postoperative surveillance program after surgical resection, the clinical effectiveness of such surveillance, which is not standardized, is questionable. Critical review of the use of different components (laboratory, radiographic, and endoscopic) of these programs finds little support for intensive surveillance.

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