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Athanassiades P, Athanassiadou P, Davaris P, et al. Changes of chromosomes 1, 3, 6, and 11 in metastatic effusions arising from breast and ovarian cancer. Cancer Genet Cytogenet. 1999;110(1):34-40doi: 10.1016/s0165-4608(98)00172-1.
Athanassiades, P., Athanassiadou, P., Davaris, P., Gagos, S., Gogas, J., Ioakim-Liossi, A., & Markopoulos, C. (1999). Changes of chromosomes 1, 3, 6, and 11 in metastatic effusions arising from breast and ovarian cancer. Cancer genetics and cytogenetics, 110(1), 34-40. https://doi.org/10.1016/s0165-4608(98)00172-1
Athanassiades, P, et al. "Changes of chromosomes 1, 3, 6, and 11 in metastatic effusions arising from breast and ovarian cancer." Cancer genetics and cytogenetics vol. 110,1 (1999): 34-40. doi: https://doi.org/10.1016/s0165-4608(98)00172-1
Athanassiades P, Athanassiadou P, Davaris P, Gagos S, Gogas J, Ioakim-Liossi A, Markopoulos C. Changes of chromosomes 1, 3, 6, and 11 in metastatic effusions arising from breast and ovarian cancer. Cancer Genet Cytogenet. 1999 Apr;110(1):34-40. doi: 10.1016/s0165-4608(98)00172-1. PMID: 10198620.
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Elsevier Science

Cancer Genet Cytogenet. 1999 Apr;110(1):34-40. doi: 10.1016/s0165-4608(98)00172-1.

Changes of chromosomes 1, 3, 6, and 11 in metastatic effusions arising from breast and ovarian cancer.

Cancer genetics and cytogenetics

P Athanassiades, P Athanassiadou, P Davaris, S Gagos, J Gogas, A Ioakim-Liossi, C Markopoulos

Affiliations

  1. Department of Pathology, Athens School of Medicine, University of Athens, Greece.

PMID: 10198620 DOI: 10.1016/s0165-4608(98)00172-1

Abstract

This cytogenetic study deals with cell material obtained from 15 pleural fluids from 11 patients with breast cancer and 27 ascitic fluids from 16 patients with ovarian cancer; in addition, 8 pleural, 5 ascitic, and 1 pericardial fluid from patients with tuberculosis, liver cirrhosis, and heart insufficiency, were studied. Using mainly direct methods, as well as short-term cell cultures, the chromosome spreads were GTG-banded. Cancerous biopsies showed a plethora of numerical and structural chromosome anomalies and exhibited broad aneuploidy. Chromosomes participating more often in numerical and structural aberrations were 1, 3, 6, 7, 8, 9, 11, 12, and 17. This study provides further cytogenetic evidence for the involvement of these chromosomes in breast and ovarian malignancy.

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