Display options
Cite
Mattia JI, Zimmerman M. Psychotic subtyping of major depressive disorder and posttraumatic stress disorder. J Clin Psychiatry. 1999;60(5):311-4doi: 10.4088/jcp.v60n0508.
Mattia, J. I., & Zimmerman, M. (1999). Psychotic subtyping of major depressive disorder and posttraumatic stress disorder. The Journal of clinical psychiatry, 60(5), 311-4. https://doi.org/10.4088/jcp.v60n0508
Mattia, J I, and Zimmerman, M. "Psychotic subtyping of major depressive disorder and posttraumatic stress disorder." The Journal of clinical psychiatry vol. 60,5 (1999): 311-4. doi: https://doi.org/10.4088/jcp.v60n0508
Mattia JI, Zimmerman M. Psychotic subtyping of major depressive disorder and posttraumatic stress disorder. J Clin Psychiatry. 1999 May;60(5):311-4. doi: 10.4088/jcp.v60n0508. PMID: 10362439.
Copy Download .nbib Format: NLM
Share it on
Full text links
Physicians Postgraduate Press, Inc.

J Clin Psychiatry. 1999 May;60(5):311-4. doi: 10.4088/jcp.v60n0508.

Psychotic subtyping of major depressive disorder and posttraumatic stress disorder.

The Journal of clinical psychiatry

J I Mattia, M Zimmerman

Affiliations

  1. Department of Psychiatry and Human Behavior, Brown University School of Medicine, Rhode Island Hospital, Providence 02905, USA. [email protected]

PMID: 10362439 DOI: 10.4088/jcp.v60n0508

Abstract

BACKGROUND: Many studies have established that a large percentage of patients with posttraumatic stress disorder (PTSD) have comorbid major depressive disorder. Other studies have found that patients with PTSD or a history of childhood trauma have an increased rate of psychotic symptoms. In the present report from the Rhode Island Methods to Improve Diagnosis and Services project, we examine whether an association exists between psychotic subtyping of major depressive disorder and PTSD.

METHOD: Five hundred psychiatric outpatients were interviewed with the Structured Clinical Interview for DSM-IV.

RESULTS: Almost half of the 500 patients had nonbipolar major depressive disorder (N = 235, 47.0%), 45 (19.1%) of whom had PTSD. Nineteen patients had psychotic depression, 216 had nonpsychotic depression. Compared with patients with nonpsychotic depression, the patients with psychotic depression were nearly 4 times more likely to have PTSD (57.9% vs. 15.7%, Fisher exact test, p = .0001).

CONCLUSION: The results of the present study suggest that the presence of psychosis in psychiatric outpatients with major depressive disorder is associated with concurrent PTSD. It is hypothesized that the poorer longitudinal course of psychotic versus nonpsychotic depression may be due to the underrecognition of PTSD in psychotically depressed patients.

Cited by

MeSH terms

Publication Types

LinkOut - more resources