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Showing 1 to 12 of 1887 entries
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Arterial blood-pressure change and endogenous circulating substance P in man.

Clinical physiology (Oxford, England)

Henriksen JH, Kastrup J, Schaffalitzky De Muckadell OB.
PMID: 2412752
Clin Physiol. 1985 Aug;5(4):377-81. doi: 10.1111/j.1475-097x.1985.tb00758.x.

Substance P (SP) is a powerful vasodilator and this peptide is today considered to be a chemical messenger. The potential effects on circulating SP of acute changes in arterial blood-pressure was investigated in nine subjects. An increase in arterial...

Prostaglandins enhance trigeminal substance P-ergic responses in the rabbit iris sphincter muscles.

Brain research

Ueda N, Muramatsu I, Fujiwara M.
PMID: 2411336
Brain Res. 1985 Jul 01;337(2):347-51. doi: 10.1016/0006-8993(85)90073-3.

Contractile responses due to substance P released from the trigeminal nerve were observed after electrical transmural stimulation or exogenous application of bradykinin in the isolated rabbit iris sphincter muscle. Prostaglandins, particulary prostaglandin E1, enhanced and indomethacin inhibited these substance...

[GABAergic neurons in the mammalian intestine].

Nihon yakurigaku zasshi. Folia pharmacologica Japonica

Taniyama K.
PMID: 2411644
Nihon Yakurigaku Zasshi. 1985 May;85(5):305-13. doi: 10.1254/fpj.85.305.

Most of the criteria for identification of a neurotransmitter were satisfied for gamma-aminobutyric acid (GABA) in the mammalian intestine. GABA and its synthesizing enzyme, glutamic acid decarboxylase, and the neurons which specifically accumulate GABA were demonstrated to localize in...

Tachykinin involvement in cutaneous anaphylaxis in the guinea pig.

Canadian journal of physiology and pharmacology

Hamel R, Ford-Hutchinson AW, Blazejczak C, Van den Brekel A.
PMID: 2468407
Can J Physiol Pharmacol. 1988 Nov;66(11):1361-7. doi: 10.1139/y88-223.

Permeability changes in the guinea-pig skin following intradermal (i.d.) injection of tachykinin agonists or antigen were monitored through the extravasation of 99mTc-labelled human serum albumin and blood flow changes through the accumulation of 51Cr-labelled microspheres. A variety of synthetic...

Neurotransmitters and the fifth cranial nerve: is there a relation to the headache phase of migraine?.

Lancet (London, England)

Moskowitz MA, Reinhard JF, Romero J, Melamed E, Pettibone DJ.
PMID: 90971
Lancet. 1979 Oct 27;2(8148):883-5. doi: 10.1016/s0140-6736(79)92692-8.

The headache phase of migraine may develop as the result of an abnormal interaction (and perhaps an abnormal release) of vasoactive neurotransmitters from terminals of the trigeminal nerve with large intracranial and extracranial blood-vessels. These blood-vessels, which dilate during...

Effects of the unilateral nigral modulation of substance P transmission on the activity of the two nigro-striatal dopaminergic pathways.

Life sciences

Michelot R, Leviel V, Giorguieff-Chesselet MF, Chéramy A, Glowinski J.
PMID: 86931
Life Sci. 1979 Feb 19;24(8):715-23. doi: 10.1016/0024-3205(79)90353-9.

No abstract available.

Evidence for a role of nigral gamma-aminobutyric acid and substance P in the haloperidol-induced activation of striatal tyrosine hydroxylase.

The Journal of pharmacology and experimental therapeutics

Gale K, Costa E, Toffano G, Hong JS, Guidotti A.
PMID: 26799
J Pharmacol Exp Ther. 1978 Jul;206(1):29-37.

No abstract available.

Brain and gut.

Clinics in endocrinology and metabolism

Powell D, Skrabanek P.
PMID: 225070
Clin Endocrinol Metab. 1979 Jul;8(2):299-312. doi: 10.1016/s0300-595x(79)80043-2.

No abstract available.

Hypothesis: the nervous system may contribute to the pathophysiology of rheumatoid arthritis.

The Journal of rheumatology

Levine JD, Collier DH, Basbaum AI, Moskowitz MA, Helms CA.
PMID: 2413204
J Rheumatol. 1985 Jun;12(3):406-11.

No current theory of the mechanisms involved in the pathophysiology of rheumatoid arthritis (RA) explains its important clinical features. We hypothesize that neural mechanisms are involved in this pathophysiology and they explain at least 3 clinical features: specific high...

Target regulation of the serotonin and substance P innervation of the sexually dimorphic cremaster nucleus.

Brain research

Newton BW, Hamill RW.
PMID: 2470469
Brain Res. 1989 Apr 17;485(1):149-56. doi: 10.1016/0006-8993(89)90676-8.

The effects of perinatal castrations on the serotonin (5-HT) and substance P (SP) innervation patterns of the adult male cremaster nucleus (CN) were examined in Sprague-Dawley rats. These investigations reveal that day-of-birth bilateral castration precludes cremaster muscle formation, significantly...

Evidence that a substance P-like peptide mediates the non-cholinergic excitatory response of the carp intestinal bulb (Cyprinus carpio).

Naunyn-Schmiedeberg's archives of pharmacology

Kitazawa T, Kudo K, Ishigami M, Furuhashi H, Temma K, Kondo H.
PMID: 2467211
Naunyn Schmiedebergs Arch Pharmacol. 1988 Jul;338(1):68-73. doi: 10.1007/BF00168814.

The participation of substance P in the noncholinergic contraction induced by transmural stimulation (TMS) of the carp intestinal bulb was examined. In the presence of atropine, substance P caused the contraction of carp intestinal bulb smooth muscle in a...

An electrophysiological comparison of substance P-immunoreactive neurons with other neurons in the guinea-pig submucous plexus.

Journal of the autonomic nervous system

Bornstein JC, Furness JB, Costa M.
PMID: 2470805
J Auton Nerv Syst. 1989 Mar;26(2):113-20. doi: 10.1016/0165-1838(89)90159-8.

Intracellular microelectrodes containing the dye Lucifer yellow CH were used to record from nerve cells of ganglia in isolated preparations of submucosa from the guinea-pig small intestine. The electrophysiological properties of the neurons were investigated by passing intracellular current...

Showing 1 to 12 of 1887 entries