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Showing 1 to 12 of 1697 entries
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A limited sampling strategy for cyclophosphamide pharmacokinetics.

Cancer research

Egorin MJ, Forrest A, Belani CP, Ratain MJ, Abrams JS, Van Echo DA.
PMID: 2720671
Cancer Res. 1989 Jun 01;49(11):3129-33.
Free Article

A limited sampling strategy was developed to estimate the total area under the curve of plasma cyclophosphamide concentrations versus time (AUC). The strategy was developed with a training set consisting of 29 pharmacokinetic studies in 16 patients who received...

[Adjuvant chemotherapy of soft tissue sarcoma].

Gan to kagaku ryoho. Cancer & chemotherapy

Shinohara N, Yokoyama K.
PMID: 2301950
Gan To Kagaku Ryoho. 1990 Feb;17(2):198-204.

As the adjuvant chemotherapy of osteosarcoma has been proved highly effective, that of soft tissue sarcoma has been expecting. However, there is still some question as to its effectiveness. The indication and methods were studied on literatures and our...

[Successful treatment of disseminated breast cancer with combination therapy of 5'-deoxy-5'-fluorouridine (5'-DFUR), medroxyprogesterone acetate (MPA) and cyclophosphamide (CPA)].

Gan to kagaku ryoho. Cancer & chemotherapy

Takatsuka Y, Katoh T, Tsumura I, Kobayakawa K, Kawahara T.
PMID: 1530905
Gan To Kagaku Ryoho. 1992 Jan;19(1):107-10.

A 54 year-old female patient with disseminated breast cancer refractory to various kinds of previous therapies was treated with a combination therapy of 5'-DFUR, MPA and CPA. Partial response (PR) was obtained both against pleural and liver metastases with...

Pilot study of a rapid etoposide-cisplatin regimen in paediatric soft tissue sarcomas.

European journal of cancer (Oxford, England : 1990)

Phillips MB, Pinkerton CR.
PMID: 1591053
Eur J Cancer. 1992;28(2):399-403. doi: 10.1016/s0959-8049(05)80062-0.

10 patients with refractory or relapsed soft tissue sarcoma were treated with weekly etoposide (150 mg/m2 on days 1, 2 and 3) and cisplatin (60 mg/m2 on day 2). Toxicity was mainly myelosuppression which resulted in deviation from planned...

[Accomplishments of tumor surgery in soft tissue sarcoma in childhood].

Langenbecks Archiv fur Chirurgie

Schweizer P, Treuner J.
PMID: 3236978
Langenbecks Arch Chir. 1988;525-9.

Malignant soft tissue tumors, a group of neoplasms with various biological characteristics, have been of oncologic interest only for the last 20 years. More than half of all soft tissue sarcomas are Rhabdomyosarcomas (RMS). Extensive comparative therapy studies have...

Cyclophosphamide versus ifosfamide: preliminary report of a randomized phase II trial in adult soft tissue sarcomas.

Cancer chemotherapy and pharmacology

Bramwell VH, Mouridsen HT, Santoro A, Blackledge G, Somers R, Thomas D, Sylvester R, Van Oosterom A.
PMID: 3102089
Cancer Chemother Pharmacol. 1986;18:S13-6. doi: 10.1007/BF00647440.

One hundred and seventy-one patients with advanced soft tissue sarcoma entered a randomized crossover phase II study comparing cyclophosphamide (CYCLO) with a new analogue, ifosfamide (IFOS), both administered as 24 h i.v. infusions every 3 weeks. The doses used...

1H NMR spectroscopy of subcutaneous tumors in mice: preliminary studies of effects of growth, chemotherapy and blood flow reduction.

NMR in biomedicine

Shungu DC, Bhujwalla ZM, Wehrle JP, Glickson JD.
PMID: 1333262
NMR Biomed. 1992 Sep-Oct;5(5):296-302. doi: 10.1002/nbm.1940050517.

This study evaluates a number of methods for obtaining 1H NMR spectra with adequate suppression of lipid and water resonances in two subcutaneously implanted transplantable tumor models (RIF-1 and EMT6/SF). Spin-echo spectra with long TEs (270 ms; water suppressed...

[Locoregional chemotherapy in neoplasms].

Minerva chirurgica

Gennari L, Quagliuolo V, Bignami P.
PMID: 1323063
Minerva Chir. 1992 Jun 30;47(12):1079-90.

Intra-arterial chemotherapy of carcinoma increases drug concentration at the level of the tumour and reduces systemic toxicity. It is being used in the treatment of solid tumours in various parts of the body with increasingly encouraging results. It can...

Cisplatin in isolated limb perfusion.

American journal of surgery

Roseman JM.
PMID: 2919745
Am J Surg. 1989 Mar;157(3):366. doi: 10.1016/0002-9610(89)90571-0.

No abstract available.

[Bolus and maintenance infusion of high-dose methotrexate].

Gan to kagaku ryoho. Cancer & chemotherapy

Amino K, Kawaguchi N, Matsumoto S, Manabe J, Tabata D, Machida M.
PMID: 2730094
Gan To Kagaku Ryoho. 1989 May;16(5):2045-9.

For 17 patients with bone and soft tissue sarcoma, 32 bolus and maintenance infusions of high-dose methotrexate (MTX) were performed to induce rapid elevation of plasma MTX concentration and to maintain it. At the doses of 200-300 mg/kg, plasma...

[Bone and soft-tissue tumors].

Gan to kagaku ryoho. Cancer & chemotherapy

Shirai Y, Nakase T.
PMID: 3002285
Gan To Kagaku Ryoho. 1986 Jan;13(1):30-6.

There have been great advances in recent years in the treatment of malignant bone and soft-tissue tumors thanks to advanced diagnostic techniques, improved chemotherapy and improved surgery involving extensive resection of the area involved, with bone and joint replacement....

Rhabdomyosarcoma of the appendicular skeleton: survival and treatment considerations.

La Chirurgia degli organi di movimento

Lane J, Ghavimi F, Exelby P, Mandell L, Mullins K, Bernstein J.
PMID: 2249520
Chir Organi Mov. 1990;75(1):163-5.

No abstract available.

Showing 1 to 12 of 1697 entries