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Showing 1 to 12 of 351261 entries
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Human parvovirus B19 and arthritis.

Behring Institute Mitteilungen

Woolf AD.
PMID: 2171489
Behring Inst Mitt. 1990 Aug;(85):64-8.

Parvovirus B19 has different clinical manifestations dependent on age and sex. In children it is usually a mild febrile exanthematous illness but in adults 60% of women and 30% of men have an arthropathy which may be severe and...

Receptor-mediated action of hepoxilin A3 releases diacylglycerol and arachidonic acid from human neutrophils.

Biochemical and biophysical research communications

Nigam S, Nodes S, Cichon G, Corey EJ, Pace-Asciak CR.
PMID: 2171511
Biochem Biophys Res Commun. 1990 Sep 28;171(3):944-8. doi: 10.1016/0006-291x(90)90775-i.

We have previously shown that hepoxilin A3 increases the intracellular concentration of Ca+2 in human neutrophils. Herein we address the initial events of hepoxilin action on the neutrophil which precede the rise in intracellular calcium. We show that hepoxilin...

A method for the correction of drift in movement analysis.

Computer methods and programs in biomedicine

Stokes VP.
PMID: 1873996
Comput Methods Programs Biomed. 1991 Apr;34(4):275-81. doi: 10.1016/0169-2607(91)90112-7.

A method is proposed for the correction of drift over cyclic three-dimensional kinematic data during treadmill locomotion. An adaptive least-squares drift correction algorithm (ALSDC) is developed from the operational definition of no drift. This method includes automatic selection of...

Calculation of site affinity constants and cooperativity coefficients for binding of ligands and/or protons to macromolecules. I. Generation of partition functions and mass balance equations.

Biophysical chemistry

Fisicaro E, Braibanti A, Lamb JD, Oscarson JL.
PMID: 2207268
Biophys Chem. 1990 May;36(1):1-14. doi: 10.1016/0301-4622(90)85001-m.

The thermodynamics of binding of a ligand A and/or proton H to a macromolecule M is treated by the partition function method. In complex systems, the representation of the equilibria by means of cumulative constants beta PQR used as...

Pharmacokinetics of aditoprim in goats using a radioassay.

Biopharmaceutics & drug disposition

Iqbal MP, Mahboobali N, Niazi SK, Mahmood MA.
PMID: 2207303
Biopharm Drug Dispos. 1990 Aug-Sep;11(6):533-41. doi: 10.1002/bdd.2510110607.

A simple, highly sensitive radioassay was developed for the activity of a newly discovered inhibitor of dihydrofolate reductase (DHFR), aditoprim. The procedure is based on the inhibition of binding of [3H]-methotrexate ([3H]MTX) with bacterial dihydrofolate reductase by the antifolate,...

Vasopressin uptake by hypothalamopituitary axis and pineal gland in guinea pigs.

The American journal of physiology

Zlokovic BV, Hyman S, McComb JG, Tang G, Rezai AR, Weiss MH.
PMID: 1902062
Am J Physiol. 1991 Apr;260(4):E633-40. doi: 10.1152/ajpendo.1991.260.4.E633.

The uptake of circulating arginine vasopressin (AVP) by the pituitary gland (anterior lobe), pineal gland, and hypothalamus (ventromedial part) was investigated in an isolated in situ perused brain of anesthetized guinea pig. Kinetic experiments revealed saturable AVP uptake in...

Dermatitis herpetiformis and gluten sensitive enteropathy (including celiac disease)--increased subepithelial extracellular matrix viscosity due to gliadin.

Medical hypotheses

Stone OJ.
PMID: 2090932
Med Hypotheses. 1990 Dec;33(4):283-8. doi: 10.1016/0306-9877(90)90143-3.

It is now firmly established that dermatitis herpetiformis (DH) is associated with gluten sensitive enteropathy (GSE), although the GSE of DH is generally milder than that form which occurs in celiac disease. The toxic fraction of gluten is in...

Sex, power laws, and HIV transmission.

Journal of acquired immune deficiency syndromes

Blower SM, Samuel MC, Wiley JA.
PMID: 1588497
J Acquir Immune Defic Syndr (1988). 1992;5(6):633-4.

No abstract available.

The role of inverted duplication in the generation of gene amplification in mammalian cells.

Biochimica et biophysica acta

Fried M, Feo S, Heard E.
PMID: 1932107
Biochim Biophys Acta. 1991 Oct 08;1090(2):143-55. doi: 10.1016/0167-4781(91)90095-4.

No abstract available.

Development of light dissemination in the rat lens after in vivo exposure to radiation in the 300-nm wavelength region.

Ophthalmic research

Söderberg PG.
PMID: 2090981
Ophthalmic Res. 1990;22(5):271-9. doi: 10.1159/000267035.

The course of development of light dissemination was investigated for rat lenses exposed in vivo to 30 kJ/m2 ultraviolet radiation (UVR) in the 300-nm wavelength region. After an initial latency phase the light dissemination increases rapidly. At 72 h...

Potential error in the measurement of tissue to blood distribution coefficients in physiological pharmacokinetic modeling. Residual tissue blood. I. Theoretical considerations.

Drug metabolism and disposition: the biological fate of chemicals

Khor SP, Mayersohn M.
PMID: 1676658
Drug Metab Dispos. 1991 Mar-Apr;19(2):478-85.

Physiological pharmacokinetic models require the determination of tissue to blood distribution coefficients. A theoretical model has been developed and the resulting equations indicate that under certain conditions it is necessary to correct for the presence of drug in the...

Two distinct effects of recombinant human tumor necrosis factor-alpha on osteoclast development and subsequent resorption of mineralized matrix.

Endocrinology

van der Pluijm G, Most W, van der Wee-Pals L, de Groot H, Papapoulos S, Löwik C.
PMID: 1874190
Endocrinology. 1991 Sep;129(3):1596-604. doi: 10.1210/endo-129-3-1596.

The multifunctional cytokine tumor necrosis factor-alpha (TNF alpha) stimulates osteoclastic resorption. It is not known which steps in osteoclast formation are affected by TNF alpha. We have investigated the effects of recombinant human TNF alpha (rhTNF alpha) on osteoclast...

Showing 1 to 12 of 351261 entries