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Showing 1 to 12 of 203 entries
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Droplet Size-Aware and Error-Correcting Sample Preparation Using Micro-Electrode-Dot-Array Digital Microfluidic Biochips.

IEEE transactions on biomedical circuits and systems

Li Z, Lai KY, Chakrabarty K, Ho TY, Lee CY.
PMID: 28976321
IEEE Trans Biomed Circuits Syst. 2017 Dec;11(6):1380-1391. doi: 10.1109/TBCAS.2017.2742548. Epub 2017 Sep 29.

Sample preparation in digital microfluidics refers to the generation of droplets with target concentrations for on-chip biochemical applications. In recent years, digital microfluidic biochips (DMFBs) have been adopted as a platform for sample preparation. However, there remain two major...

Optimization and evaluation of radially interconnected versus bifurcating flow distributors using computational fluid dynamics modelling.

Journal of chromatography. A

Davydova E, Deridder S, Eeltink S, Desmet G, Schoenmakers PJ.
PMID: 25591402
J Chromatogr A. 2015 Feb 06;1380:88-95. doi: 10.1016/j.chroma.2014.12.063. Epub 2014 Dec 30.

Two main groups of flow distributors, viz. "bifurcating distributors" (BF) and "radially interconnected distributors" (RI), as well as some hybrid distributors were investigated. Computational fluid dynamics was used to evaluate the performance of the distributors and to establish the...

Correlated electrical and optical analysis of single nanoparticles and biomolecules on a nanopore-gated optofluidic chip.

Nano letters

Liu S, Zhao Y, Parks JW, Deamer DW, Hawkins AR, Schmidt H.
PMID: 25006747
Nano Lett. 2014 Aug 13;14(8):4816-20. doi: 10.1021/nl502400x. Epub 2014 Jul 11.

The analysis of individual biological nanoparticles has significantly advanced our understanding of fundamental biological processes but is also rapidly becoming relevant for molecular diagnostic applications in the emerging field of personalized medicine. Both optical and electrical methods for the...

Experimental investigation and computational modeling of hydrodynamics in bifurcating microchannels.

Biomedical microdevices

Janakiraman V, Sastry S, Kadambi JR, Baskaran H.
PMID: 18175219
Biomed Microdevices. 2008 Jun;10(3):355-65. doi: 10.1007/s10544-007-9143-6.

Methods involving microfluidics have been used in several chemical, biological and medical applications. In particular, a network of bifurcating microchannels can be used to distribute flow in a large space. In this work, we carried out experiments to determine...

Micromixer utilizing electrokinetic instability-induced shedding effect.

Electrophoresis

Tai CH, Yang RJ, Huang MZ, Liu CW, Tsai CH, Fu LM.
PMID: 17109376
Electrophoresis. 2006 Dec;27(24):4982-90. doi: 10.1002/elps.200500900.

This paper presents a T-shaped micromixer featuring 45 degrees parallelogram barriers (PBs) within the mixing channel. The presented device obtains a rapid mixing of two sample fluids with conductivity ratio of 10:1 (sample concentration:running buffer concentration) by means of...

Labs-on-a-Chip: origin, highlights and future perspectives. On the occasion of the 10th microTAS conference.

Lab on a chip

van den Berg A, Bergveld P.
PMID: 17102838
Lab Chip. 2006 Oct;6(10):1266-73. doi: 10.1039/b612120a. Epub 2006 Sep 14.

No abstract available.

Electrospray ionization from a gap with adjustable width.

Rapid communications in mass spectrometry : RCM

Ek P, Sjödahl J, Roeraade J.
PMID: 17016803
Rapid Commun Mass Spectrom. 2006;20(21):3176-82. doi: 10.1002/rcm.2710.

In this paper, we present a new concept for electrospray ionization mass spectrometry, where the sample is applied in a gap which is formed between the edges of two triangular-shaped tips. The size of the spray orifice can be...

Effect of nonuniform surface potential on electroosmotic flow at large applied electric field strength.

Biomedical microdevices

Chen L, Conlisk AT.
PMID: 18850273
Biomed Microdevices. 2009 Feb;11(1):251-8. doi: 10.1007/s10544-008-9231-2.

Electroosmotic flow in nanochannels with non-uniform wall potential is investigated. While several researchers have presented results for the case of periodic potential and sudden change in potential, most of the previous work in this area is based on the...

Numerical studies of electrokinetic control of DNA concentration in a closed-end microchannel.

Electrophoresis

Daghighi Y, Li D.
PMID: 20191548
Electrophoresis. 2010 Mar;31(5):868-78. doi: 10.1002/elps.200900447.

A major challenge in lab-on-a-chip devices is how to concentrate sample molecules from a dilute solution, which is critical to the effectiveness and the detection limit of on-chip bio-chemical reactions. A numerical study of sample concentration control by electrokinetic...

Returning to diagnostic basics.

BioTechniques

Webb SA.
PMID: 20629269
Biotechniques. 2010 Jul;49(1):491-3. doi: 10.2144/000113461.

No abstract available.

Microfluidics: bridges between two worlds.

Nature nanotechnology

Eijkel J, van den Berg A.
PMID: 20523334
Nat Nanotechnol. 2010 Jun;5(6):387-8. doi: 10.1038/nnano.2010.113.

No abstract available.

Micro and nano technologies in Bioanalysis. Preface.

Methods in molecular biology (Clifton, N.J.)

Lee JW, Foote RS.
PMID: 19771672
Methods Mol Biol. 2009;544:v-vii.

No abstract available.

Showing 1 to 12 of 203 entries