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Showing 1 to 12 of 102 entries
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Characterisation of a micro-plasma for ambient mass spectrometry imaging.

The Analyst

Bowfield A, Bunch J, Salter TL, Steven RT, Gilmore IS, Barrett DA, Alexander MR, McKay K, Bradley JW.
PMID: 25142127
Analyst. 2014 Nov 07;139(21):5430-8. doi: 10.1039/c4an01110d.

Results are presented on the characterisation and optimisation of a non-thermal atmospheric pressure micro-plasma ion source used for ambient mass spectrometry imaging. The geometry of the experiment is optimised to produce the most intense and stable ion signals. Signal...

Good mass spectrometry and its place in good science.

Journal of mass spectrometry : JMS

Duncan MW.
PMID: 22707172
J Mass Spectrom. 2012 Jun;47(6):795-809. doi: 10.1002/jms.3038.

The mass spectrometry community has expanded as instruments became more powerful, user-friendly, affordable and readily available. This opens up opportunities for novice users to perform high impact research, using highly advanced instrumentation. This introductory tutorial is targeted at the...

FastTrack to supercritical fluid chromatographic purification: Implementation of a walk-up analytical supercritical fluid chromatography/mass spectrometry screening system in the medicinal chemistry laboratory.

Journal of chromatography. A

Aurigemma C, Farrell W.
PMID: 20728893
J Chromatogr A. 2010 Sep 24;1217(39):6110-4. doi: 10.1016/j.chroma.2010.07.066. Epub 2010 Aug 03.

Medicinal chemists often depend on analytical instrumentation for reaction monitoring and product confirmation at all stages of pharmaceutical discovery and development. To obtain pure compounds for biological assays, the removal of side products and final compounds through purification is...

LC-MS-based metabolomics.

Molecular bioSystems

Zhou B, Xiao JF, Tuli L, Ressom HW.
PMID: 22041788
Mol Biosyst. 2012 Feb;8(2):470-81. doi: 10.1039/c1mb05350g. Epub 2011 Nov 01.

Metabolomics aims at identification and quantitation of small molecules involved in metabolic reactions. LC-MS has enjoyed a growing popularity as the platform for metabolomic studies due to its high throughput, soft ionization, and good coverage of metabolites. The success...

Pathos: a web facility that uses metabolic maps to display experimental changes in metabolites identified by mass spectrometry.

Rapid communications in mass spectrometry : RCM

Leader DP, Burgess K, Creek D, Barrett MP.
PMID: 22002696
Rapid Commun Mass Spectrom. 2011 Nov 30;25(22):3422-6. doi: 10.1002/rcm.5245.

This work describes a freely available web-based facility which can be used to analyse raw or processed mass spectrometric data from metabolomics experiments and display the metabolites identified--and changes in their experimental abundance--in the context of the metabolic pathways...

Biomedical mass spectrometry.

Analytical and bioanalytical chemistry

Nakanishi T, Setou M, Kuhara T.
PMID: 22488109
Anal Bioanal Chem. 2012 Jun;403(7):1775-6. doi: 10.1007/s00216-012-5922-x.

No abstract available.

Mass spectrometers for the analysis of biomolecules.

Methods in enzymology

Baldwin MA.
PMID: 16401505
Methods Enzymol. 2005;402:3-48. doi: 10.1016/S0076-6879(05)02001-X.

Mass spectrometry (MS) has become a vital enabling technology in the life sciences. This chapter summarizes the fundamental aspects of MS, with reference to topics such as isotopic abundance and accurate mass and resolution. A broad and comprehensive overview...

Capillary electrophoresis - mass spectrometry: survey on developments and applications 2003-2004.

Electrophoresis

Schmitt-Kopplin P, Englmann M.
PMID: 15776480
Electrophoresis. 2005 Apr;26(7):1209-20. doi: 10.1002/elps.200410355.

The major developments and applications related to CE-MS over the last two years (2003-2004) and most of the reviews and applications found in the ISI Web of Science and publisher data bases are presented in a tabulated way. This...

High-field asymmetric waveform ion mobility spectrometry: a new tool for mass spectrometry.

Journal of chromatography. A

Guevremont R.
PMID: 15595648
J Chromatogr A. 2004 Nov 26;1058(1):3-19.

High-field asymmetric waveform ion mobility spectrometry (FAIMS) is a new technology for ion separation at atmospheric pressure. This review introduces the reader to FAIMS, covering topics ranging from the fundamentals and extraction of physical parameters from the raw data,...

Developing an understanding of proteomics: an introduction to biological mass spectrometry.

Cancer investigation

Koomen J, Hawke D, Kobayashi R.
PMID: 15779868
Cancer Invest. 2005;23(1):47-59.

Three components form the foundation of the rapidly growing field of proteomics research: traditional protein chemistry experiments, separations science, and biological mass spectrometry. The increasing demand for proteomics, as well as the presentation of the 2003 Nobel Prize to...

A mass spectrometry primer for mass spectrometry imaging.

Methods in molecular biology (Clifton, N.J.)

Rubakhin SS, Sweedler JV.
PMID: 20680583
Methods Mol Biol. 2010;656:21-49. doi: 10.1007/978-1-60761-746-4_2.

Mass spectrometry imaging (MSI), a rapidly growing subfield of chemical imaging, employs mass spectrometry (MS) technologies to create single- and multi-dimensional localization maps for a variety of atoms and molecules. Complimentary to other imaging approaches, MSI provides high chemical...

Corra: Computational framework and tools for LC-MS discovery and targeted mass spectrometry-based proteomics.

BMC bioinformatics

Brusniak MY, Bodenmiller B, Campbell D, Cooke K, Eddes J, Garbutt A, Lau H, Letarte S, Mueller LN, Sharma V, Vitek O, Zhang N, Aebersold R, Watts JD.
PMID: 19087345
BMC Bioinformatics. 2008 Dec 16;9:542. doi: 10.1186/1471-2105-9-542.

BACKGROUND: Quantitative proteomics holds great promise for identifying proteins that are differentially abundant between populations representing different physiological or disease states. A range of computational tools is now available for both isotopically labeled and label-free liquid chromatography mass spectrometry...

Showing 1 to 12 of 102 entries