Display options
Filter resources
Text Availability
Article type
Publication date
Showing 1 to 12 of 9025 entries
Sorted by: Best Match Show Resources per page
Orally absorbable cephalosporin antibiotics. 3. Preparation of biologically active R isomer of 7-(3-benzothienylglycylamido)deacetoxycephalosporanic acid.

Journal of medicinal chemistry

Kukolja S, Pfeil JL, Draheim SE, Ott JL.
PMID: 2933520
J Med Chem. 1985 Dec;28(12):1903-6. doi: 10.1021/jm00150a024.

The methyl and isopropyl esters of (RS)-3-benzothienylglycine were resolved with (+)- and (-)-tartaric acid in acetonitrile to give the corresponding R and S salts. The R-salt 4 was hydrolyzed to (R)-3-benzothienylglycine (5). The amino group in 5 was protected...

[In vitro evaluation of the antibiotic effect of imipenen on bacterial strains isolated mostly from compromised patients].

Quaderni Sclavo di diagnostica clinica e di laboratorio

Bartolucci M, Galluzzi F, Sanchioni G, Aureli G.
PMID: 3268913
Quad Sclavo Diagn. 1988 Jan-Dec;24(1):203-12.

The antibacterial activity in vitro of Imipenem (N-formimidoyl-thienamycin) was studied on 237 recently-isolated nosocomial bacterial strains and compared with Aztreonam, Cefotaxime, Ceftazidime, Ceftriaxone, Piperacillin, Amikacin and Netilmicin through the determination of susceptibility by the Kirby-Bauer method. Taking into account...

Chloropolysporins A, B and C, novel glycopeptide antibiotics from Faenia interjecta sp. nov. V. Comparative studies of the biological properties.

The Journal of antibiotics

Takatsu T, Katayama T, Nakajima M, Takahashi S, Haneishi T, Magaribuchi T, Tajima M.
PMID: 3624073
J Antibiot (Tokyo). 1987 Jul;40(7):946-52. doi: 10.7164/antibiotics.40.946.

Chloropolysporins A, B and C, as well as derivatives prepared from this group and alpha- and beta-avoparcins by enzymatic and mild acid hydrolysis, were active against Gram-positive bacteria including clinically isolated methicillin-resistant Staphylococci (MIC 0.39-6.25 micrograms/ml) and anaerobic enterobacteria...

Estimation of gram-negative bacteria in milk: a comparison of inhibitor systems for preventing gram-positive bacterial growth.

The Journal of applied bacteriology

Phillips JD, Griffiths MW.
PMID: 3745029
J Appl Bacteriol. 1986 Jun;60(6):491-500. doi: 10.1111/j.1365-2672.1986.tb01088.x.

A number of inhibitor systems which have been reported to allow selection of Gram-negative bacteria were tested against Gram-positive and Gram-negative isolates of dairy origin. No one system worked perfectly. A mixture of crystal violet-penicillin-nisin or monensin had least...

Worldwide assessment of the activity of cefotetan against clinical isolates.

Chemioterapia : international journal of the Mediterranean Society of Chemotherapy

Turner PJ, Edwards JR.
PMID: 3180309
Chemioterapia. 1988 Aug;7(4):274-7.

Data on the antibacterial activity of cefotetan collected since 1985 have been compiled into a computer database and an analysis of results on more than 100,000 clinical isolates presented. The studies were conducted in 285 hospitals located throughout Europe,...

Aminothiazolylglycyl derivatives of carbacephems. I. Synthesis and antibacterial activity of novel carbacephems with substituted aminothiazolyl groups.

The Journal of antibiotics

Mochida K, Shiraki C, Yamasaki M, Hirata T, Sato K, Okachi R.
PMID: 3558115
J Antibiot (Tokyo). 1987 Jan;40(1):14-21. doi: 10.7164/antibiotics.40.14.

A series of new carbacephem compounds which have substituted aminothiazolylglycyl side chain have been prepared starting from corresponding carbacephems with aminothiazolylmethoxyimino group. Among them, the compound having 3,4-dihydroxybenzoyl group showed very sharp activity against Pseudomonas aeruginosa. Moreover, the optical...

Glaucium flavum Crantz. IV. Antimicrobial activity.


Cabo J, Cabo MM, Cabo MP, Cruz T, Ruiz C.
PMID: 3241575
Microbios. 1988;56(228):177-80.

The extracts obtained from root, stem, leaf and fruit pericarps of Glaucium flavum showed antibacterial activity in an in vitro assay. The root extract was the most active against the Gram-positive bacteria which were investigated.

In-vitro antibacterial activity of DQ-2556 and its stability to various beta-lactamases.

The Journal of antimicrobial chemotherapy

Fujimoto T, Watanabe M, Inoue M, Mitsuhashi S.
PMID: 2228824
J Antimicrob Chemother. 1990 Sep;26(3):329-41. doi: 10.1093/jac/26.3.329.

DQ-2556, a new cephalosporin, showed a broad antibacterial spectrum over Gram-positive and -negative organisms. The activity of DQ-2556 against recent clinical isolates of Gram-positive cocci and Enterobacteriaceae was comparable with that of cefpirome, and superior to that of ceftazidime....

[The antimicrobial activity of Augmentin (amoxicillin/clavulanic acid) compared to other antibacterial agents].

Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]

Zubkov MN, Nonikov VE, Gugutsidze EN, Sutormina TM, Makarova OV.
PMID: 1444669
Antibiot Khimioter. 1992 Sep;37(9):34-6.

Sensitivity of clinical strains of gram-positive and gram-negative bacteria to Augmentin was studied in comparison to other antibiotics. Augmentin was shown to be advantageous in the level and spectrum of its antibacterial activity over ampicillin and other broad-spectrum antibiotics.

Bactericidal activity of meropenem and interactions with other antibiotics.

The Journal of antimicrobial chemotherapy

Ferrara A, Grassi G, Grassi FA, Piccioni PD, Gialdroni Grassi G.
PMID: 2808210
J Antimicrob Chemother. 1989 Sep;24:239-50. doi: 10.1093/jac/24.suppl_a.239.

MICs of meropenem for selected clinical isolates of bacteria were determined. Killing curves were performed on strains of methicillin-sensitive Staphylococcus aureus, methicillin-resistant Staph. aureus (MRSA), methicillin-resistant Staph, epidermidis, Escherichia coli, Klebsiella spp., Enterobacter cloacae, Pseudomonas aeruginosa, Citrobacter freundii and...

Hydroxylation and N-demethylation of clarithromycin (6-O-methylerythromycin A) by Mucor circinelloides.

The Journal of antibiotics

Adachi T, Sasaki J, Omura S.
PMID: 2529234
J Antibiot (Tokyo). 1989 Sep;42(9):1433-7. doi: 10.7164/antibiotics.42.1433.

No abstract available.

1,2,3-triazolo[4,5-f]quinolines. II. Preparation and antimicrobial evaluation of 6-ethyl-6,9-dihydro-1(2)(3)-R-1(2) (3)H-triazolo [4,5-f]quinolin-9-one-8-carboxylic acids as anti-infectives of the urinary tract (1).

Farmaco (Societa chimica italiana : 1989)

Nuvole A, Sanna P, Paglietti G, Juliano C, Zanetti S, Cappuccinelli P.
PMID: 2553038
Farmaco. 1989 Jun;44(6):619-32.

Some 6-ethyl-1(2)(3)-R-1(2)(3)H-triazolo[4,5-f]quinolin-9-one-8-carboxy lic acids were prepared as novel analogues of oxolinic acid in order to evaluate the effect on antibacterial activity of the isosteric replacement of the dioxolic moiety with the triazole ring substituted in position 1 or 2....

Showing 1 to 12 of 9025 entries