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Showing 1 to 12 of 60 entries
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Protein Composition Reflects Extracellular Vesicle Heterogeneity.

Proteomics

Vagner T, Chin A, Mariscal J, Bannykh S, Engman DM, Di Vizio D.
PMID: 30793499
Proteomics. 2019 Apr;19(8):e1800167. doi: 10.1002/pmic.201800167. Epub 2019 Apr 02.

Extracellular vesicles (EVs) are membrane-enclosed particles that are released by virtually all cells from all living organisms. EVs shuttle biologically active cargo including protein, RNA, and DNA between cells. When shed by cancer cells, they function as potent intercellular...

[Advances of Exosomes Extraction and Its Mechanism in Early Diagnosis of Lung Cancer].

Zhongguo fei ai za zhi = Chinese journal of lung cancer

Luo D, Li C, Wu L, Chen Q.
PMID: 32752584
Zhongguo Fei Ai Za Zhi. 2020 Nov 20;23(11):999-1006. doi: 10.3779/j.issn.1009-3419.2020.101.24. Epub 2020 Aug 05.

Lung cancer is a malignant tumor with high incidence and mortality in the world, which seriously threatens people's safety and health. Early diagnosis of lung cancer is the key part in the process of prevention and treatment of lung...

Exosomes as Targeted Drug Delivery Vehicles: Perspectives and Challenges.

Current drug metabolism

Liu D, Li X.
PMID: 32614741
Curr Drug Metab. 2020;21(5):329. doi: 10.2174/138920022105200701160418.

No abstract available.

Comparison and Investigation of Exosomes Derived from Platelet-Rich Plasma Activated by Different Agonists.

Cell transplantation

Rui S, Yuan Y, Du C, Song P, Chen Y, Wang H, Fan Y, Armstrong DG, Deng W, Li L.
PMID: 34006140
Cell Transplant. 2021 Jan-Dec;30:9636897211017833. doi: 10.1177/09636897211017833.

PRP-Exos are nanoscale cup-shaped vesicles that carry a variety of proteins, mRNAs, microRNAs, and other bioactive substances. PRP-Exos can be formed through several induction pathways, which determine their molecular profiles and facilitate their tailormade participation in intercellular communication. Currently,...

Targeting Stem Cells in Chronic Inflammatory Diseases.

Advances in experimental medicine and biology

van de Vyver M, Powrie YSL, Smith C.
PMID: 33725353
Adv Exp Med Biol. 2021;1286:163-181. doi: 10.1007/978-3-030-55035-6_12.

Mesenchymal stem cell (MSC) dysfunction is a serious complication in ageing and age-related inflammatory diseases such as type 2 diabetes mellitus. Inflammation and oxidative stress-induced cellular senescence alter the immunomodulatory ability of MSCs and hamper their pro-regenerative function, which...

[Significance of exosomes in cardiology: heralds of cardioprotection].

Archivos de cardiologia de Mexico

Arroyo-Campuzano M, Zazueta C.
PMID: 33661872
Arch Cardiol Mex. 2021;91(1):105-113. doi: 10.24875/ACM.20000335.

Los exosomas tienen un papel clave en la comunicación intercelular. Debido a sus múltiples interacciones, estas estructuras cumplen con el papel de «mensajeros» de forma dinámica, transportando su contenido a células blanco específicas y generando nuevas señales celulares. En...

Critical Review of the Evolution of Extracellular Vesicles' Knowledge: From 1946 to Today.

International journal of molecular sciences

Bazzan E, Tinè M, Casara A, Biondini D, Semenzato U, Cocconcelli E, Balestro E, Damin M, Radu CM, Turato G, Baraldo S, Simioni P, Spagnolo P, Saetta M, Cosio MG.
PMID: 34203956
Int J Mol Sci. 2021 Jun 15;22(12). doi: 10.3390/ijms22126417.

Extracellular vesicles (EVs) are a family of particles/vesicles present in blood and body fluids, composed of phospholipid bilayers that carry a variety of molecules that can mediate cell communication, modulating crucial cell processes such as homeostasis, induction/dampening of inflammation,...

Clinical Implications of Exosomes: Targeted Drug Delivery for Cancer Treatment.

International journal of molecular sciences

Massey AE, Malik S, Sikander M, Doxtater KA, Tripathi MK, Khan S, Yallapu MM, Jaggi M, Chauhan SC, Hafeez BB.
PMID: 34067896
Int J Mol Sci. 2021 May 17;22(10). doi: 10.3390/ijms22105278.

Exosomes are nanoscale vesicles generated by cells for intercellular communication. Due to their composition, significant research has been conducted to transform these particles into specific delivery systems for various disease states. In this review, we discuss the common isolation...

Commentary: Cardiosphere-derived exosomes for single-ventricle heart disease: Are some of the parts greater than the whole?.

The Journal of thoracic and cardiovascular surgery

Vekstein AM, Turek JW, Andersen ND.
PMID: 33246569
J Thorac Cardiovasc Surg. 2021 Sep;162(3):990-991. doi: 10.1016/j.jtcvs.2020.08.033. Epub 2020 Aug 15.

No abstract available.

Exosomal miRNAs in tumor microenvironment.

Journal of experimental & clinical cancer research : CR

Tan S, Xia L, Yi P, Han Y, Tang L, Pan Q, Tian Y, Rao S, Oyang L, Liang J, Lin J, Su M, Shi Y, Cao D, Zhou Y, Liao Q.
PMID: 32299469
J Exp Clin Cancer Res. 2020 Apr 16;39(1):67. doi: 10.1186/s13046-020-01570-6.

Tumor microenvironment (TME) is the internal environment in which tumor cells survive, consisting of tumor cells, fibroblasts, endothelial cells, and immune cells, as well as non-cellular components, such as exosomes and cytokines. Exosomes are tiny extracellular vesicles (40-160nm) containing...

Rapid and label-free cancer theranostics .

Materials horizons

Semcheddine F, El Islem Guissi N, Liu W, Tayyaba, Gang L, Jiang H, Wang X.
PMID: 34605844
Mater Horiz. 2021 Oct 04;8(10):2771-2784. doi: 10.1039/d1mh00880c.

Chemically engineered nanomaterials have been extensively used in early tumor detection and cancer therapy. Despite the promise shown, their chemical or exogenous nature hinders their application due to their unknown adverse effects. Herein, using a cancer cell environment, fluorescent...

Exosomes: From Functions in Host-Pathogen Interactions and Immunity to Diagnostic and Therapeutic Opportunities.

Reviews of physiology, biochemistry and pharmacology

Carrière J, Barnich N, Nguyen HT.
PMID: 27600934
Rev Physiol Biochem Pharmacol. 2016;172:39-75. doi: 10.1007/112_2016_7.

Since their first description in the 1980s, exosomes, small endosomal-derived extracellular vesicles, have been involved in innate and adaptive immunity through modulating immune responses and mediating antigen presentation. Increasing evidence has reported the role of exosomes in host-pathogen interactions...

Showing 1 to 12 of 60 entries