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Introduction for the special issue on recent advances in drug delivery across tissue barriers.

Tissue barriers

Mrsny RJ, Brayden DJ.
PMID: 27358759
Tissue Barriers. 2016 Jun 07;4(2):e1187981. doi: 10.1080/21688370.2016.1187981. eCollection 2016.

This special issue of Tissue Barriers contains a series of reviews with the common theme of how biological barriers established at epithelial tissues limit the uptake of macromolecular therapeutics. By improving our functional understanding of these barriers, the majority...

Predicting the Reliability of Drug-target Interaction Predictions with Maximum Coverage of Target Space.

Scientific reports

Peón A, Naulaerts S, Ballester PJ.
PMID: 28630414
Sci Rep. 2017 Jun 19;7(1):3820. doi: 10.1038/s41598-017-04264-w.

Many computational methods to predict the macromolecular targets of small organic molecules have been presented to date. Despite progress, target prediction methods still have important limitations. For example, the most accurate methods implicitly restrict their predictions to a relatively...

Stem cells as drug delivery methods: application of stem cell secretome for regeneration.

Advanced drug delivery reviews

Tran C, Damaser MS.
PMID: 25451858
Adv Drug Deliv Rev. 2015 Mar;82:1-11. doi: 10.1016/j.addr.2014.10.007. Epub 2014 Oct 15.

Mesenchymal stem cells (MSCs) are a unique cell population defined by their ability to indefinitely self-renew, differentiate into multiple cell lineages, and form clonal cell populations. It was originally thought that this ability for broad plasticity defined the therapeutic...

Where is the drug gone? Measuring intracellular delivery and localization.

Methods (San Diego, Calif.)

Ryadnov MG.
PMID: 24935255
Methods. 2014 Jul 01;68(2):281-2. doi: 10.1016/j.ymeth.2014.06.001.

No abstract available.

Lessons in simplicity that should shape the future of drug delivery.

Nature biotechnology

Raemdonck K, De Smedt SC.
PMID: 26448080
Nat Biotechnol. 2015 Oct;33(10):1026-7. doi: 10.1038/nbt.3366.

No abstract available.

Preface.

Current drug delivery

Toth I.
PMID: 27447004
Curr Drug Deliv. 2016;13(1):3. doi: 10.2174/156720181301160314153150.

No abstract available.

Editorial.

Planta medica

Bilia AR, Bergonzi MC.
PMID: 28297733
Planta Med. 2017 Mar;83(5):365. doi: 10.1055/s-0043-101989. Epub 2017 Mar 15.

No abstract available.

Magnetic Resonance-Guided Drug Delivery.

Magnetic resonance imaging clinics of North America

Mikhail AS, Partanen A, Yarmolenko P, Venkatesan AM, Wood BJ.
PMID: 26499281
Magn Reson Imaging Clin N Am. 2015 Nov;23(4):643-55. doi: 10.1016/j.mric.2015.05.012. Epub 2015 Jul 09.

The use of clinical imaging modalities for the guidance of targeted drug delivery systems, known as image-guided drug delivery (IGDD), has emerged as a promising strategy for enhancing antitumor efficacy. MR imaging is particularly well suited for IGDD applications...

Patrick Couvreur: inspiring pharmaceutical innovation.

Nanomedicine (London, England)

Stanwix H.
PMID: 24981648
Nanomedicine (Lond). 2014 May;9(6):759-61. doi: 10.2217/nnm.14.24.

Patrick Couvreur speaks to Hannah Stanwix, Managing Comissioning Editor: Professor Patrick Couvreur received his pharmacy degree from the Université Catholique de Louvain (Louvain-la-Neuve, Belgium) in 1972. He holds a PhD in pharmaceutical technology from the same university and completed...

In pursuit of functional electrospun materials for clinical applications in humans.

Therapeutic delivery

Stoddard RJ, Steger AL, Blakney AK, Woodrow KA.
PMID: 27250537
Ther Deliv. 2016 Jun;7(6):387-409. doi: 10.4155/tde-2016-0017. Epub 2016 Jun 02.

Electrospinning is a simple, low-cost and versatile approach to fabricate multifunctional materials useful in drug delivery and tissue engineering applications. Despite its emergence into other manufacturing sectors, electrospinning has not yet made a transformative impact in the clinic with...

Retrometabolic approaches for drug design and targeting.

Die Pharmazie

Bodor N.
PMID: 9266587
Pharmazie. 1997 Jul;52(7):491-4.

Retrometabolic drug design approaches incorporate targeting and metabolic considerations into the drug design process and represent a novel, systematic methodology for the design of safe, localized compounds. Two major design concepts aimed to increase the therapeutic index (the activity/toxicity...

Mathematical modeling of controlled drug delivery.

Advanced drug delivery reviews

Siepmann J, Peppas NA.
PMID: 11369078
Adv Drug Deliv Rev. 2001 Jun 11;48(2):137-8. doi: 10.1016/s0169-409x(01)00111-9.

No abstract available.

Showing 1 to 12 of 201 entries