Display options
Filter resources
Text Availability
Article type
Publication date
Showing 1 to 12 of 70673 entries
Sorted by: Best Match Show Resources per page
Therapeutic implications of tumor physiology.

Current opinion in oncology

Jain RK.
PMID: 1843113
Curr Opin Oncol. 1991 Dec;3(6):1105-8. doi: 10.1097/00001622-199112000-00020.

The advent of genetic engineering and hybridoma technology has led to the design and large-scale production of various novel therapeutic agents for the treatment of cancer. However, these agents have not yet realized their clinical potential, presumably due to...

[Locoregional therapy in patients with malignant pleural effusion--two different types of "BAC therapy"].

Gan to kagaku ryoho. Cancer & chemotherapy

Sugitachi A, Kawahara T, Kido T, Shindoh T.
PMID: 1530324
Gan To Kagaku Ryoho. 1992 Aug;19(10):1640-3.

We used fibrin clot (FC) as a carrier of anticancer drug (AD) to provide a novel therapy for patients with serious malignant pleural effusion. After evacuating the pleural fluid, we enhanced an "FC-AD" formation in the pleural cavity of...

[Targeting cancer chemotherapy using temperature-sensitive liposomes containing adriamycin conjugated with monoclonal antibodies].

Gan to kagaku ryoho. Cancer & chemotherapy

Shibata S, Kumai K, Takahashi T, Murayama Y, Ishibiki K, Kitajima M.
PMID: 1530328
Gan To Kagaku Ryoho. 1992 Aug;19(10):1671-4.

Liposomes have a specific liquid-crystalline phase transition temperature (Tc), at which they release an entrapped drug. Temperature-sensitive liposomes containing adriamycin (TS-Lip-ADM) were made of dipalmitoylphosphatidylcholine (DPPC, Tc: 41 degrees C), distearoylphosphatidylcholine (DSPC, Tc: 54 degrees C), cholesterol and adriamycin....

[The comparison of absorptive routes of intraperitoneal infusion with cisplatin in dogs].

Gan to kagaku ryoho. Cancer & chemotherapy

Namatame K, Kou Y, Sasaki E, Nakayoshi A.
PMID: 1530339
Gan To Kagaku Ryoho. 1992 Aug;19(10):1716-9.

Dogs weighing between 10 and 15 kg were used, and cisplatin was given at a dose of 2 mg/kg. The dogs were infused ip with either 100 ml (A groups) or 200 ml (B groups) of physiological salt solution...

Surface-modulated skin layers of thermal responsive hydrogels as on-off switches: I. Drug release.

Journal of biomaterials science. Polymer edition

Yoshida R, Sakai K, Ukano T, Sakurai Y, Bae YH, Kim SW.
PMID: 1768636
J Biomater Sci Polym Ed. 1991;3(2):155-62. doi: 10.1163/156856291x00250.

Thermosensitive co-polymers of isopropyl acrylamide (IPAAm) with butyl methacrylate (BMA) are capable of 'on-off' regulation of drug release in response to external temperature changes due to skin formation with increasing temperature. To clarify the role of the surface-modulated skin...

Polymethylmethacrylate-antiblastic drug compounds: an in vitro study assessing the cytotoxic effect in cancer cell lines--a new method for local chemotherapy of bone metastasis.


Greco F, de Palma L, Specchia N, Jacobelli S, Gaggini C.
PMID: 1738721
Orthopedics. 1992 Feb;15(2):189-94.

An in vitro study was performed assessing the pharmacologic properties of polymethylmethacrylate (PMMA)-antiblastic agent (doxorubicin and cisplatinum) mixtures in normal and neoplastic cell lines cultures. The study's aim was to analyze the polymerization capacity of PMMA in the presence...

Ciprofloxacin-impregnated poly-L-lactic acid drug carrier. New aspects of a resorbable drug delivery system in local antimicrobial treatment of bone infections.

Archives of orthopaedic and trauma surgery

Teupe C, Meffert R, Winckler S, Ritzerfeld W, Törmälä P, Brug E.
PMID: 1482616
Arch Orthop Trauma Surg. 1992;112(1):33-5. doi: 10.1007/BF00431041.

Resorbable poly-L-lactic acid (PLLA) cylinders (3.5 mm diameter, 5 mm in length) carrying 6% of weight ciprofloxacin (Ciprobay, Bayer AG, Leverkusen, FRG) were investigated in vitro to explore their properties as a slow-release antibiotic deposit. Forty bioactive cylinders stored...

Slow-release delivery systems.

The Practitioner

Squire I, Lees K.
PMID: 1305755
Practitioner. 1992 Nov;236(1520):1088-91.

No abstract available.

Transdermal estradiol. A review of its pharmacological profile, and therapeutic potential in the prevention of postmenopausal osteoporosis.

Drugs & aging

Balfour JA, McTavish D.
PMID: 1493353
Drugs Aging. 1992 Nov-Dec;2(6):487-507. doi: 10.2165/00002512-199202060-00005.

The estradiol transdermal therapeutic system is a percutaneous delivery device which, when affixed to the skin, delivers estradiol (the major estrogen in premenopausal women) into the systemic circulation at a constant rate for up to 4 days. Because this...

A theoretical analysis of a new drug delivery system: a cylindrical device with a vertical opening on its surface.

Journal of pharmaceutical sciences

Hsu JP, Ting C, Lin MJ.
PMID: 1432630
J Pharm Sci. 1992 Sep;81(9):866-70. doi: 10.1002/jps.2600810905.

A theoretical analysis of a proposed drug delivery device is presented. The device is of cylindrical shape with an opening on its side surface. Analytical expressions for the temporal variations in the amount of drug released and the size...

Chemistry and biology of immunotargeted liposomes.

Targeted diagnosis and therapy

Weiner AL.
PMID: 2131015
Targeted Diagn Ther. 1990;3:305-36.

No abstract available.

Immunoconjugates in drug delivery systems.

Targeted diagnosis and therapy

Cannon JB, Hui HW.
PMID: 2131008
Targeted Diagn Ther. 1990;3:121-39.

No abstract available.

Showing 1 to 12 of 70673 entries