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Loss of allelic heterozygosity on distal chromosome 1p in Merkel cell carcinoma. A marker of neural crest origins?.

Cancer genetics and cytogenetics

Harnett PR, Kearsley JH, Hayward NK, Dracopoli NC, Kefford RF.
PMID: 1676609
Cancer Genet Cytogenet. 1991 Jul 01;54(1):109-13. doi: 10.1016/0165-4608(91)90037-u.

The location of genes involved in tumor evolution has been inferred from experiments in which loss of constitutional heterozygosity has been detected in tumor DNA at high frequency in specific chromosome regions. For example, cytogenetic and molecular abnormalities on...

Child with deletion of 4q and duplication of 1q.

American journal of medical genetics

Wade J, Morgan T, Allanson J.
PMID: 2596517
Am J Med Genet. 1989 Aug;33(4):553-4. doi: 10.1002/ajmg.1320330430.

No abstract available.

Apparent Fryns syndrome in a boy with a tandem duplication of 1q24-31.2.

American journal of medical genetics

Clark RD, Fenner-Gonzales M.
PMID: 2596530
Am J Med Genet. 1989 Nov;34(3):422-6. doi: 10.1002/ajmg.1320340319.

We report on a newborn boy with manifestations of Fryns syndrome who also had a mosaic tandem duplication of chromosome 1q24-31.2. The child had a diaphragmatic hernia, cleft palate, hypoplastic and absent digits, micrognathia, long philtrum, thin upper lip,...

1p13 is the most frequently involved band in structural chromosomal rearrangements in human breast cancer.

Genes, chromosomes & cancer

Mitchell EL, Santibanez-Koref MF.
PMID: 2268577
Genes Chromosomes Cancer. 1990 Nov;2(4):278-89. doi: 10.1002/gcc.2870020405.

Cytogenetic data on 14 breast carcinomas were examined to determine which chromosome arms and bands are preferentially involved in structural chromosome changes. Chromosome arms 17p, 16q, and 1p and band 1p13 were found to be significantly involved. A review...

A presumptive translocation 1p;2q resulting in duplication 1p and deletion 2q.

American journal of medical genetics

Halal F, Vekemans M, Der Kaloustian VM.
PMID: 2658588
Am J Med Genet. 1989 Mar;32(3):376-9. doi: 10.1002/ajmg.1320320322.

Here we report on a girl with a translocation between 1 and 2 and duplication 1p and deletion 2q resulting in a multiple congenital anomaly syndrome including intrauterine growth retardation, microcephaly, hypotelorism, cleft palate, subglottic stenosis, umbilical hernia, scoliosis,...

The segregation of a translocation t(1;4) in two male carriers heterozygous for the translocation.

Human genetics

Estop AM, Levinson F, Cieply K, Vankirk V.
PMID: 1618491
Hum Genet. 1992 Jun;89(4):425-9. doi: 10.1007/BF00194315.

We examined the meiotic segregation pattern of a t(1;4)(p36.2;q31.3) reciprocal translocation in two male cousins heterozygous for the translocation. The wife of subject 1 had four recognized spontaneous abortions and two carrier daughters, and the wife of subject 2...

[Partial trisomy 1q25-1q32 in a boy with isolated lactase deficiency].

Ceskoslovenska pediatrie

Franková Y, Zeman J, Mejsnarová B, Stloukalová M, Pajerek J.
PMID: 2119894
Cesk Pediatr. 1990 Feb;45(2):87-8.

A six-month-old boy with partial trisomia 1q25-1q32. In the phenotype psychomotor retardation, progeric facial features and general dystrophy dominated. He failed to thrive partly because of milk intolerance due to hypolactasia. This disorder was revealed by histochemical examination of...

Six genes of the human connexin gene family coding for gap junctional proteins are assigned to four different human chromosomes.

European journal of cell biology

Willecke K, Jungbluth S, Dahl E, Hennemann H, Heynkes R, Grzeschik KH.
PMID: 1964417
Eur J Cell Biol. 1990 Dec;53(2):275-80.

Connexin genes code for proteins that form cell-to-cell channels known as gap junctions. The genes for the known connexins 26, 32, 43, and 46 have been assigned to human chromosomes, 13, X, 6, and 13, respectively, by analysis of...

A translocation (1;10)(p32;q24) in a neuroblastoma cell line derived from marrow metastases.

Cancer genetics and cytogenetics

Skinnider L, Wang SY, Wang HC, Krespin HI.
PMID: 2302681
Cancer Genet Cytogenet. 1990 Mar;45(1):131-5. doi: 10.1016/0165-4608(90)90076-m.

Chromosomes of a cell line derived from neuroblastoma metastases were analysed. Ninety-nine percent of the cells had 46 chromosomes, and of 10 cells analysed by G-banding, all had a t(1;10)(p32;q24).

Two distinct mechanisms for the SCL gene activation in the t(1;14) translocation of T-cell leukemias.

Genes, chromosomes & cancer

Bernard O, Guglielmi P, Jonveaux P, Cherif D, Gisselbrecht S, Mauchauffe M, Berger R, Larsen CJ, Mathieu-Mahul D.
PMID: 1964581
Genes Chromosomes Cancer. 1990 Jan;1(3):194-208. doi: 10.1002/gcc.2870010303.

Molecular study of a t(1;14)(p32;q11) translocation found in an acute T-cell leukemia (Kd cells) with a relatively mature phenotype is reported. Complex DNA rearrangements were characterized in the TCR alpha/delta locus. Besides a productive V alpha/J alpha assembly found...

Chromosome 1 studies in Wilms' tumor.

Cancer genetics and cytogenetics

McDowell H, Howard P, Martin J, Hart C, Crampton J.
PMID: 2557151
Cancer Genet Cytogenet. 1989 Dec;43(2):203-9. doi: 10.1016/0165-4608(89)90031-9.

Ten newly diagnosed patients with Wilms' tumor had blood and tumor samples taken for cytogenetic analysis. DNA was also extracted from these samples, along with blood obtained from both parents and an age- and sex-matched control. Molecular biological techniques...

A dinucleotide repeat polymorphism at the D1S116 locus.

Nucleic acids research

Sharma V, Allen L, Magenis RE, Litt M.
PMID: 2020559
Nucleic Acids Res. 1991 Mar 11;19(5):1169.
Free PMC Article

No abstract available.

Showing 1 to 12 of 7659 entries