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Showing 1 to 12 of 19 entries
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Medicinal Chemists of the 21(st) Century--Who Are We and Where to Go?.

ChemMedChem

Nussbaumer P.
PMID: 25924977
ChemMedChem. 2015 Jul;10(7):1133-9. doi: 10.1002/cmdc.201500133. Epub 2015 Apr 29.

Many recent articles have dealt with the future challenges in medicinal chemistry. Here, I discuss my concerns over the future of medicinal chemists, who have to be skilled and knowledgeable in many different fields, particularly in the context of...

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Nussbaumer P. Medicinal Chemists of the 21(st) Century--Who Are We and Where to Go?. ChemMedChem. 2015;10(7):1133-9doi: 10.1002/cmdc.201500133.
Nussbaumer, P. (2015). Medicinal Chemists of the 21(st) Century--Who Are We and Where to Go?. ChemMedChem, 10(7), 1133-9. https://doi.org/10.1002/cmdc.201500133
Nussbaumer, Peter. "Medicinal Chemists of the 21(st) Century--Who Are We and Where to Go?." ChemMedChem vol. 10,7 (2015): 1133-9. doi: https://doi.org/10.1002/cmdc.201500133
Nussbaumer P. Medicinal Chemists of the 21(st) Century--Who Are We and Where to Go?. ChemMedChem. 2015 Jul;10(7):1133-9. doi: 10.1002/cmdc.201500133. Epub 2015 Apr 29. PMID: 25924977.
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Embedding sustainable practices into pharmaceutical R&D: what are the challenges?.

Future medicinal chemistry

Sneddon H.
PMID: 25329193
Future Med Chem. 2014;6(12):1373-6. doi: 10.4155/fmc.14.91.

No abstract available.

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Sneddon H. Embedding sustainable practices into pharmaceutical R&D: what are the challenges?. Future Med Chem. 2014;6(12):1373-6doi: 10.4155/fmc.14.91.
Sneddon, H. (2014). Embedding sustainable practices into pharmaceutical R&D: what are the challenges?. Future medicinal chemistry, 6(12), 1373-6. https://doi.org/10.4155/fmc.14.91
Sneddon, Helen. "Embedding sustainable practices into pharmaceutical R&D: what are the challenges?." Future medicinal chemistry vol. 6,12 (2014): 1373-6. doi: https://doi.org/10.4155/fmc.14.91
Sneddon H. Embedding sustainable practices into pharmaceutical R&D: what are the challenges?. Future Med Chem. 2014;6(12):1373-6. doi: 10.4155/fmc.14.91. PMID: 25329193.
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For medicinal purposes.

Nature

Petsko GA.
PMID: 8895592
Nature. 1996 Nov 07;384(6604):7-9. doi: 10.1038/384007a0.

Developments in techniques of pharmaceutical chemistry are poised to revolutionize the design of drugs beyond previous expectations. But what are our current expectations and what does the future hold?

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Petsko GA. For medicinal purposes. Nature. 1996;384(6604):7-9doi: 10.1038/384007a0.
Petsko, G. A. (1996). For medicinal purposes. Nature, 384(6604), 7-9. https://doi.org/10.1038/384007a0
Petsko, G A. "For medicinal purposes." Nature vol. 384,6604 (1996): 7-9. doi: https://doi.org/10.1038/384007a0
Petsko GA. For medicinal purposes. Nature. 1996 Nov 07;384(6604):7-9. doi: 10.1038/384007a0. PMID: 8895592.
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Chris Lipinski discusses life and chemistry after the Rule of Five.

Drug discovery today

Lipinski CA.
PMID: 12546981
Drug Discov Today. 2003 Jan 01;8(1):12-6. doi: 10.1016/s1359-6446(02)02556-4.

No abstract available.

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Lipinski CA. Chris Lipinski discusses life and chemistry after the Rule of Five. Drug Discov Today. 2003;8(1):12-6doi: 10.1016/s1359-6446(02)02556-4.
Lipinski, C. A. (2003). Chris Lipinski discusses life and chemistry after the Rule of Five. Drug discovery today, 8(1), 12-6. https://doi.org/10.1016/s1359-6446(02)02556-4
Lipinski, Christopher A. "Chris Lipinski discusses life and chemistry after the Rule of Five." Drug discovery today vol. 8,1 (2003): 12-6. doi: https://doi.org/10.1016/s1359-6446(02)02556-4
Lipinski CA. Chris Lipinski discusses life and chemistry after the Rule of Five. Drug Discov Today. 2003 Jan 01;8(1):12-6. doi: 10.1016/s1359-6446(02)02556-4. PMID: 12546981.
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Chemistry outsourcing going global.

Nature reviews. Drug discovery

Frantz S.
PMID: 16802442
Nat Rev Drug Discov. 2006 May;5(5):362-3. doi: 10.1038/nrd2049.

No abstract available.

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Frantz S. Chemistry outsourcing going global. Nat Rev Drug Discov. 2006;5(5):362-3doi: 10.1038/nrd2049.
Frantz, S. (2006). Chemistry outsourcing going global. Nature reviews. Drug discovery, 5(5), 362-3. https://doi.org/10.1038/nrd2049
Frantz, Simon. "Chemistry outsourcing going global." Nature reviews. Drug discovery vol. 5,5 (2006): 362-3. doi: https://doi.org/10.1038/nrd2049
Frantz S. Chemistry outsourcing going global. Nat Rev Drug Discov. 2006 May;5(5):362-3. doi: 10.1038/nrd2049. PMID: 16802442.
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Simon Campbell on the ups and downs of drug discovery and development. Interview by Jayne Carey and Samantha Barton.

Drug discovery today

Campbell S.
PMID: 15708739
Drug Discov Today. 2005 Feb 15;10(4):233-6. doi: 10.1016/S1359-6446(04)03366-5.

Simon Campbell discusses his role in the development of sildenafil and doxazosin, as well as his current role as President of the RSC. Campbell goes on to give his opinions on how technological advances are influencing the changing roles...

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Campbell S. Simon Campbell on the ups and downs of drug discovery and development. Interview by Jayne Carey and Samantha Barton. Drug Discov Today. 2005;10(4):233-6doi: 10.1016/S1359-6446(04)03366-5.
Campbell, S. (2005). Simon Campbell on the ups and downs of drug discovery and development. Interview by Jayne Carey and Samantha Barton. Drug discovery today, 10(4), 233-6. https://doi.org/10.1016/S1359-6446(04)03366-5
Campbell, Simon. "Simon Campbell on the ups and downs of drug discovery and development. Interview by Jayne Carey and Samantha Barton." Drug discovery today vol. 10,4 (2005): 233-6. doi: https://doi.org/10.1016/S1359-6446(04)03366-5
Campbell S. Simon Campbell on the ups and downs of drug discovery and development. Interview by Jayne Carey and Samantha Barton. Drug Discov Today. 2005 Feb 15;10(4):233-6. doi: 10.1016/S1359-6446(04)03366-5. PMID: 15708739.
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Efficient medicinal chemistry.

Combinatorial chemistry & high throughput screening

Kyle DJ.
PMID: 16475964
Comb Chem High Throughput Screen. 2006 Feb;9(2):77. doi: 10.2174/138620706775541909.

No abstract available.

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Kyle DJ. Efficient medicinal chemistry. Comb Chem High Throughput Screen. 2006;9(2):77doi: 10.2174/138620706775541909.
Kyle, D. J. (2006). Efficient medicinal chemistry. Combinatorial chemistry & high throughput screening, 9(2), 77. https://doi.org/10.2174/138620706775541909
Kyle, Donald J. "Efficient medicinal chemistry." Combinatorial chemistry & high throughput screening vol. 9,2 (2006): 77. doi: https://doi.org/10.2174/138620706775541909
Kyle DJ. Efficient medicinal chemistry. Comb Chem High Throughput Screen. 2006 Feb;9(2):77. doi: 10.2174/138620706775541909. PMID: 16475964.
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[Concise analysis for innovation of pioneering and follow-on drugs].

Yao xue xue bao = Acta pharmaceutica Sinica

Guo ZR.
PMID: 29897709
Yao Xue Xue Bao. 2016 Aug;51(8):1179-84.

More attention has been paid to the pioneering drug innovation since the new millennium, while the creation space of fast-followed drugs is shrinking due to the serious risks observed in the clinical phases following marketing. Innovative drug discovery aiming...

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Guo ZR. [Concise analysis for innovation of pioneering and follow-on drugs]. Yao Xue Xue Bao. 2016;51(8):1179-84
Guo, Z. R. (2016). [Concise analysis for innovation of pioneering and follow-on drugs]. Yao xue xue bao = Acta pharmaceutica Sinica, 51(8), 1179-84.
Guo, Zong-ru. "[Concise analysis for innovation of pioneering and follow-on drugs]." Yao xue xue bao = Acta pharmaceutica Sinica vol. 51,8 (2016): 1179-84.
Guo ZR. [Concise analysis for innovation of pioneering and follow-on drugs]. Yao Xue Xue Bao. 2016 Aug;51(8):1179-84. Chinese. PMID: 29897709.
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Recent advances in medicinal chemistry.

Bioorganic & medicinal chemistry letters

Blagg BS, Johnson DS, Garbaccio RM.
PMID: 21513866
Bioorg Med Chem Lett. 2011 May 01;21(9):2585-6. doi: 10.1016/j.bmcl.2011.04.019.

No abstract available.

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Blagg BS, Johnson DS, Garbaccio RM. Recent advances in medicinal chemistry. Bioorg Med Chem Lett. 2011;21(9):2585-6doi: 10.1016/j.bmcl.2011.04.019.
Blagg, B. S., Johnson, D. S., & Garbaccio, R. M. (2011). Recent advances in medicinal chemistry. Bioorganic & medicinal chemistry letters, 21(9), 2585-6. https://doi.org/10.1016/j.bmcl.2011.04.019
Blagg, Brian S J, et al. "Recent advances in medicinal chemistry." Bioorganic & medicinal chemistry letters vol. 21,9 (2011): 2585-6. doi: https://doi.org/10.1016/j.bmcl.2011.04.019
Blagg BS, Johnson DS, Garbaccio RM. Recent advances in medicinal chemistry. Bioorg Med Chem Lett. 2011 May 01;21(9):2585-6. doi: 10.1016/j.bmcl.2011.04.019. PMID: 21513866.
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Women in Medicinal Chemistry: Ad Maiora!.

Journal of medicinal chemistry

Bolognesi ML, Ganamet KL, Liu H, Poulsen SA, Georg GI, Wang S.
PMID: 32078314
J Med Chem. 2020 Mar 12;63(5):1777-1778. doi: 10.1021/acs.jmedchem.0c00228. Epub 2020 Feb 20.

No abstract available.

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Bolognesi ML, Ganamet KL, Liu H, et al. Women in Medicinal Chemistry: Ad Maiora!. J Med Chem. 2020;63(5):1777-1778doi: 10.1021/acs.jmedchem.0c00228.
Bolognesi, M. L., Ganamet, K. L., Liu, H., Poulsen, S. A., Georg, G. I., & Wang, S. (2020). Women in Medicinal Chemistry: Ad Maiora!. Journal of medicinal chemistry, 63(5), 1777-1778. https://doi.org/10.1021/acs.jmedchem.0c00228
Bolognesi, Maria Laura, et al. "Women in Medicinal Chemistry: Ad Maiora!." Journal of medicinal chemistry vol. 63,5 (2020): 1777-1778. doi: https://doi.org/10.1021/acs.jmedchem.0c00228
Bolognesi ML, Ganamet KL, Liu H, Poulsen SA, Georg GI, Wang S. Women in Medicinal Chemistry: Ad Maiora!. J Med Chem. 2020 Mar 12;63(5):1777-1778. doi: 10.1021/acs.jmedchem.0c00228. Epub 2020 Feb 20. PMID: 32078314.
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Many, diverse topics have been covered in recent years in CTMC. Preface.

Current topics in medicinal chemistry

Reitz AB.
PMID: 25713821
Curr Top Med Chem. 2015;14(24):2751-7. doi: 10.2174/156802661424150105115257.

No abstract available.

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Reitz AB. Many, diverse topics have been covered in recent years in CTMC. Preface. Curr Top Med Chem. 2015;14(24):2751-7doi: 10.2174/156802661424150105115257.
Reitz, A. B. (2015). Many, diverse topics have been covered in recent years in CTMC. Preface. Current topics in medicinal chemistry, 14(24), 2751-7. https://doi.org/10.2174/156802661424150105115257
Reitz, Allen B. "Many, diverse topics have been covered in recent years in CTMC. Preface." Current topics in medicinal chemistry vol. 14,24 (2015): 2751-7. doi: https://doi.org/10.2174/156802661424150105115257
Reitz AB. Many, diverse topics have been covered in recent years in CTMC. Preface. Curr Top Med Chem. 2015;14(24):2751-7. doi: 10.2174/156802661424150105115257. PMID: 25713821.
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Fragment-to-Lead Medicinal Chemistry Publications in 2016.

Journal of medicinal chemistry

Johnson CN, Erlanson DA, Jahnke W, Mortenson PN, Rees DC.
PMID: 29087197
J Med Chem. 2018 Mar 08;61(5):1774-1784. doi: 10.1021/acs.jmedchem.7b01298. Epub 2017 Oct 31.

The popularity of fragment-based drug discovery (FBDD) is demonstrated by the number of recent successful fragment-to-lead (F2L) publications. This Miniperspective provides a tabulated summary of the F2L literature published in the year 2016, along with discussion of general trends....

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Johnson CN, Erlanson DA, Jahnke W, et al. Fragment-to-Lead Medicinal Chemistry Publications in 2016. J Med Chem. 2017;61(5):1774-1784doi: 10.1021/acs.jmedchem.7b01298.
Johnson, C. N., Erlanson, D. A., Jahnke, W., Mortenson, P. N., & Rees, D. C. (2018). Fragment-to-Lead Medicinal Chemistry Publications in 2016. Journal of medicinal chemistry, 61(5), 1774-1784. https://doi.org/10.1021/acs.jmedchem.7b01298
Johnson, Christopher N, et al. "Fragment-to-Lead Medicinal Chemistry Publications in 2016." Journal of medicinal chemistry vol. 61,5 (2018): 1774-1784. doi: https://doi.org/10.1021/acs.jmedchem.7b01298
Johnson CN, Erlanson DA, Jahnke W, Mortenson PN, Rees DC. Fragment-to-Lead Medicinal Chemistry Publications in 2016. J Med Chem. 2018 Mar 08;61(5):1774-1784. doi: 10.1021/acs.jmedchem.7b01298. Epub 2017 Oct 31. PMID: 29087197.
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Showing 1 to 12 of 19 entries