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Showing 1 to 12 of 44 entries
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CHEMICAL SYNTHESIS. Going with the flow.

Science (New York, N.Y.)

Martin RE.
PMID: 27034365
Science. 2016 Apr 01;352(6281):44-5. doi: 10.1126/science.aaf3065.

No abstract available.

Self-assembled organic nanostructures in medicinal chemistry: advances and applications.

Current topics in medicinal chemistry

Rodrigues J, Rathi B.
PMID: 25930062
Curr Top Med Chem. 2015;15(13):1161. doi: 10.2174/1568026615666150330105539.

No abstract available.

[Formulation Optimization of Zuojin Floating-Bioadhesive Pellets by Central Composite Design-Response Surface Methodology].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials

Xu F, Wang LL, Shi ZQ, Chen F, Sun DM.
PMID: 26930991
Zhong Yao Cai. 2015 Sep;38(9):1969-73.

OBJECTIVE: To optimize the formulation of Zuojin floating-bioadhesive pellets by the central composite design-response surface methodology (CCD-RSM).METHODS: In the formulation design using CCD-RSM, independent variables were the amounts of sodium bicarbonate (X1), HPMC (X2) and MCC (X3) as factors....

Preface.

Current drug delivery

Toth I.
PMID: 27447004
Curr Drug Deliv. 2016;13(1):3. doi: 10.2174/156720181301160314153150.

No abstract available.

Technical Advances in Medicinal Chemistry.

ACS combinatorial science

Finn MG.
PMID: 28374995
ACS Comb Sci. 2017 May 08;19(5):277-278. doi: 10.1021/acscombsci.7b00053. Epub 2017 Apr 04.

No abstract available.

[Possibility of New Medicinal Chemistry Based on "Wet-Dry" Interfaced Pharmaceutical Category].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan

Tokiwa H.
PMID: 26329543
Yakugaku Zasshi. 2015;135(9):1001-2. doi: 10.1248/yakushi.15-00175-F.

No abstract available.

Embedding sustainable practices into pharmaceutical R&D: what are the challenges?.

Future medicinal chemistry

Sneddon H.
PMID: 25329193
Future Med Chem. 2014;6(12):1373-6. doi: 10.4155/fmc.14.91.

No abstract available.

Role of the development scientist in compound lead selection and optimization.

Journal of pharmaceutical sciences

Venkatesh S, Lipper RA.
PMID: 10688744
J Pharm Sci. 2000 Feb;89(2):145-54. doi: 10.1002/(SICI)1520-6017(200002)89:2<145::AID-JPS2>3.0.CO;2-6.

The R&D process for bringing drugs from discovery laboratories to the marketplace is undergoing rapid change, as enabled by new technologies and as demanded by the global pharmaceutical business environment. One consequence of the accelerated R&D paradigm is a...

Chris Lipinski discusses life and chemistry after the Rule of Five.

Drug discovery today

Lipinski CA.
PMID: 12546981
Drug Discov Today. 2003 Jan 01;8(1):12-6. doi: 10.1016/s1359-6446(02)02556-4.

No abstract available.

Similarity-based virtual screening using 2D fingerprints.

Drug discovery today

Willett P.
PMID: 17129822
Drug Discov Today. 2006 Dec;11(23):1046-53. doi: 10.1016/j.drudis.2006.10.005. Epub 2006 Oct 20.

This paper summarizes recent work at the University of Sheffield on virtual screening methods that use 2D fingerprint measures of structural similarity. A detailed comparison of a large number of similarity coefficients demonstrates that the well-known Tanimoto coefficient remains...

Proceedings of the 16th annual conference of the Groupement des Pharmacochimistes de l'Arc Atlantique (GP2A).

Journal of enzyme inhibition and medicinal chemistry

Guillon J, Le Baut G, Le Borgne M.
PMID: 18821248
J Enzyme Inhib Med Chem. 2008 Oct;23(5):587. doi: 10.1080/14756360802204656.

No abstract available.

Efficient medicinal chemistry.

Combinatorial chemistry & high throughput screening

Kyle DJ.
PMID: 16475964
Comb Chem High Throughput Screen. 2006 Feb;9(2):77. doi: 10.2174/138620706775541909.

No abstract available.

Showing 1 to 12 of 44 entries