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Morphological and biochemical studies on the effect of agents with liver protecting properties.

Szepesházi K, Lapis K, Jeney A, Szende B, Schawartz J, Ujhelyi E, Takács J, Kovalszky I, Tompa A.
PMID: 729706
Exp Pathol (Jena). 1978;15(5):271-87. doi: 10.1016/s0014-4908(78)80067-2.

The liver protective effect of Aicaphosphate in CC1(4)-induced acute, as well as CC1(4)-and thioacetamide-induced subacute and chronic liver damages is demonstrated. The effect of the protective drugs was studied in the forms of pre-, simultaneous and delayed treatment in...

Mechanism of carbon tetrachloride hepatotoxicity. An in vivo study of its molecular basis in rats and monkeys.

Chopra P, Roy S, Ramalingaswami V, Nayak NC.
PMID: 4402320
Lab Invest. 1972 Jun;26(6):716-27.

No abstract available.

Further studies on the late preventive effects of the anticalmodulin trifluoperazine on carbon tetrachloride-induced liver necrosis.

Bernacchi AS, Fernández G, Villarruel MC, de Ferreyra EC, de Castro CR, de Fenos OM, Castro JA.
PMID: 3371454
Exp Mol Pathol. 1988 Jun;48(3):286-300. doi: 10.1016/0014-4800(88)90065-2.

Trifluoperazine (TFP) (50 mg/kg ip) administration to rats 6 or 10 hr after CCl4 (1 ml/kg ip in olive oil) significantly prevented liver necrosis but not fatty liver caused by the hepatotoxin at 24 hr as evidenced by either...

[Roentgenocontrast lienography in experimental diffuse liver lesions].

Bekmuratov EB, Rozenberg OA, Saĭkin VKh, Fomina EV, Khanson KP.
PMID: 3990529
Med Radiol (Mosk). 1985 Apr;30(4):10-4.

The diagnostic potentialities of i. v. lienography were studied in experiments on rodents during the administration of the liposome forms of radiographic contrast agents (RCA) in the presence of chronic diffuse liver lesion simulated by subcutaneous injection of 50%...

Sensitivity of several serum enzymes in detecting carbon tetrachloride-induced liver damage in rats.

Korsrud GO, Grice HC, McLaughlan JM.
PMID: 5041376
Toxicol Appl Pharmacol. 1972 Jul;22(3):474-83. doi: 10.1016/0041-008x(72)90255-4.

No abstract available.

Effect of 3-methylcholanthrene on hyperplastic and early neoplastic hepatic lesions induced in rats by carbon tetrachloride.

Reuber MD.
PMID: 4321181
J Natl Cancer Inst. 1970 Dec;45(6):1237-42.

No abstract available.

Histophotometric estimation of volume density of collagen as an indication of fibrosis in rat liver.

James J, Bosch KS, Zuyderhoudt FM, Houtkooper JM, van Gool J.
PMID: 3744896
Histochemistry. 1986;85(2):129-33. doi: 10.1007/BF00491759.

The development of fibrosis in the liver of 16 rats treated for 1, 2, 3 or 4 weeks with CCl4, has been followed with chemical hydroxyproline determination and histophotometric analysis of histological sections stained with Sirius Red F3BA in...

The spectrum of hepatotoxicity.

Zimmerman HJ.
PMID: 4387099
Perspect Biol Med. 1968;12(1):135-61. doi: 10.1353/pbm.1968.0004.

No abstract available.

[Hepatotoxic reactions caused by drugs].

Schmid M.
PMID: 4872262
Helv Med Acta. 1967;34(1):Suppl:15-23.

No abstract available.

Oral toxicity of carbon tetrachloride: acute, subacute, and subchronic studies in rats.

Bruckner JV, MacKenzie WF, Muralidhara S, Luthra R, Kyle GM, Acosta D.
PMID: 3710021
Fundam Appl Toxicol. 1986 Jan;6(1):16-34. doi: 10.1016/0272-0590(86)90260-5.

This investigation was conducted to characterize the acute, subacute, and subchronic toxic potency of ingested carbon tetrachloride (CCl4). In the first acute and subacute toxicity study, male Sprague-Dawley rats of 300-350 g were gavaged with 0, 20, 40, or...

Effect of long-term administration of ethanol to the rat: lipids, collagen and other proteins, and Mallory bodies in the liver.

Häkkinen HM, Franssila K, Kulonen E.
PMID: 1209162
Scand J Clin Lab Invest. 1975 Dec;35(8):753-65. doi: 10.3109/00365517509095807.

Rats drank ethanol, on the average 1.20 g/100 g body weight, for various periods up to nearly 300 days. Experimental variables included a high-fat, low-protein diet, administration of additional ethanol by stomach tube, and CCl4 injections instead of ethanol....

Protection against carbon tetrachloride hepatotoxicity by pretreatment with indole-3-carbinol.

Shertzer HG, Niemi MP, Reitman FA, Berger ML, Myers BL, Tabor MW.
PMID: 3556531
Exp Mol Pathol. 1987 Apr;46(2):180-9. doi: 10.1016/0014-4800(87)90064-5.

The effects of administering indole-3-carbinol (I-3-C) on carbon tetrachloride (CCl4)-induced hepatotoxicity were examined. Mice received by gavage 0-150 mg I-3-C/kg body wt in methanol-extracted corn oil, followed 1 h later by 15 microliters CCl4/kg body wt in corn oil....

Showing 1 to 12 of 906 entries