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Showing 1 to 12 of 8952 entries
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Behaviour of different clinical, immunological and serological parameters observed in a group of HIV positive patients during a 12 month treatment period with zidovudine.

Crocchiolo PR, Lizioli A, Arcidiacono I, Cantaluppi P, Filippi C, Sobatti D, Bedarida G, D'Agostino F, Cambie G, Nardella ML.
PMID: 1983798
Boll Ist Sieroter Milan. 1990 Jun;69(2):423-30.

During a 12 month open clinical trial, 14 patients (6 with AIDS, 2 with ARC and 6 with PGL) were continuously administered a daily 1200 mg dose of Zidovudine. Clinical course was correlated with a number of serological (HIV...

AIDS therapy and the detection of adverse drug effects in dental practice.

Arrowsmith JB.
PMID: 2592694
J Am Dent Assoc. 1989 Nov;46S-48S. doi: 10.14219/jada.archive.1989.0285.

No abstract available.

Drug information monographs for AIDS patients.

Nabors KL, Sauer BL, Soehn MS, Flynn N.
PMID: 2773953
Am J Hosp Pharm. 1989 Aug;46(8):1546-7.

No abstract available.

AIDS in Edinburgh drug users: observations on the epidemic and implications for its future management.

Flegg PJ, Brettle RP.
PMID: 1673989
J Infect. 1991 Mar;22(2):113-8. doi: 10.1016/0163-4453(91)91459-b.

We are now witnessing the anticipated explosion of cases of AIDS resulting from the epidemic of HIV infection among Edinburgh drug users in the first half of the last decade. We expect the number of new cases of AIDS...

Targets for antiviral therapy of human immunodeficiency virus infection.

Jeffries DJ.
PMID: 2464649
J Infect. 1989 Jan;18:5-13. doi: 10.1016/s0163-4453(89)80075-1.

The development of potent anti-retroviral drugs is central to the control of human immunodeficiency virus (HIV) infection and the prevention of disease. Despite the benefit (albeit limited) shown by the early trials of zidovudine in patients with acquired immune...

Predictors of outcome in AIDS patients receiving zidovudine.

Steinberg JP, Spear JB, Murphy RL, Wallemark CB, Benson CA, Kessler HA, Pottage JC, Phair JP.
PMID: 2524583
J Acquir Immune Defic Syndr (1988). 1989;2(3):229-34.

Fifty-eight AIDS patients who previously had Pneumocystis carinii pneumonia (PCP) were enrolled in an open trial of zidovudine therapy. We analyzed baseline clinical and laboratory parameters to identify predictors of outcome. Fifty-eight patients were followed for a mean of...

[New chemical compounds with antiviral action].

Herdewijn P.
PMID: 2464877
Verh K Acad Geneeskd Belg. 1988;50(4):349-65.

No abstract available.

Erythrocytosis after zidovudine for AIDS.

Kennedy CA, Griffith HS, Mathisen GE.
PMID: 1984754
Ann Intern Med. 1991 Feb 01;114(3):250-1. doi: 10.7326/0003-4819-114-3-250.

No abstract available.

Zidovudine for children.

[No authors listed]
PMID: 2349912
Am Fam Physician. 1990 Jun;41(6):1864, 1866.

No abstract available.

[The characteristics of the opportunistic infections associated with AIDS: tuberculosis and toxoplasmosis].

Gatell JM.
PMID: 2236772
Rev Clin Esp. 1990 May;186(8):405-6.

No abstract available.

Pharmacokinetics of potential anti-AIDS agents thiofoscarnet and foscarnet in the cat.

Straw JA, Loo TL, de Vera CC, Nelson PD, Tompkins WA, Bai SA.
PMID: 1387417
J Acquir Immune Defic Syndr (1988). 1992;5(9):936-42.

The pharmacokinetics of thiophosphonoformate (TPFA) and phosphonoformate (foscarnet, PFA) were studied in normal adult cats, a species susceptible to feline immunodeficiency virus (FIV) infection. Parent drugs and metabolites were quantitated by high-performance liquid chromatography (HPLC). TPFA had a mean...

Non-peptidic anti-AIDS agents: inhibition of HIV-1 proteinase by disulfonates.

Brinkworth RI, Fairlie DP.
PMID: 1445307
Biochem Biophys Res Commun. 1992 Oct 30;188(2):624-30. doi: 10.1016/0006-291x(92)91102-v.

Based upon an earlier observation that sodium docosanedioate (NaO2C-(CH2)20-CO2NA) weakly inhibits HIV-1 proteinase (IC50 12 microM), we have identified a class of more potent inhibitors (sulfonic acids) of this enzyme which are likewise dianionic at pH 5-6.5. Many of...

Showing 1 to 12 of 8952 entries