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The Effects of Age on the Pharmacokinetics and Pharmacodynamics of Cardiovascular Drugs: Application of Concentration-Effect Modeling. 1. Tolmesoxide.

American journal of therapeutics

Meredith PA, Scott PJ, Kelman AW, Hughes DM, Reid JL.
PMID: 11854822
Am J Ther. 1995 Aug;2(8):532-536. doi: 10.1097/00045391-199508000-00003.

The effects of age on the disposition and hemodynamic responses to the direct acting vasodilator tolmesoxide were examined in an integrated manner using a combined pharmacokinetic--pharmacodynamic (PKPD) modeling approach. Thirty subjects were studied to represent, as far as was...

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Meredith PA, Scott PJ, Kelman AW, et al. The Effects of Age on the Pharmacokinetics and Pharmacodynamics of Cardiovascular Drugs: Application of Concentration-Effect Modeling. 1. Tolmesoxide. Am J Ther. 1995;2(8):532-536doi: 10.1097/00045391-199508000-00003.
Meredith, P. A., Scott, P. J., Kelman, A. W., Hughes, D. M., & Reid, J. L. (1995). The Effects of Age on the Pharmacokinetics and Pharmacodynamics of Cardiovascular Drugs: Application of Concentration-Effect Modeling. 1. Tolmesoxide. American journal of therapeutics, 2(8), 532-536. https://doi.org/10.1097/00045391-199508000-00003
Meredith, P. A., et al. "The Effects of Age on the Pharmacokinetics and Pharmacodynamics of Cardiovascular Drugs: Application of Concentration-Effect Modeling. 1. Tolmesoxide." American journal of therapeutics vol. 2,8 (1995): 532-536. doi: https://doi.org/10.1097/00045391-199508000-00003
Meredith PA, Scott PJ, Kelman AW, Hughes DM, Reid JL. The Effects of Age on the Pharmacokinetics and Pharmacodynamics of Cardiovascular Drugs: Application of Concentration-Effect Modeling. 1. Tolmesoxide. Am J Ther. 1995 Aug;2(8):532-536. doi: 10.1097/00045391-199508000-00003. PMID: 11854822.
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