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Showing 1 to 5 of 5 entries
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Carbon Monoxide-Neuroglobin Axis Targeting Metabolism Against Inflammation in BV-2 Microglial Cells.

Molecular neurobiology

Dias-Pedroso D, Ramalho JS, Sardão VA, Jones JG, Romão CC, Oliveira PJ, Vieira HLA.
PMID: 34797521
Mol Neurobiol. 2021 Nov 19; doi: 10.1007/s12035-021-02630-4. Epub 2021 Nov 19.

Microglia are the immune competent cell of the central nervous system (CNS), promoting brain homeostasis and regulating inflammatory response against infection and injury. Chronic or exacerbated neuroinflammation is a cause of damage in several brain pathologies. Endogenous carbon monoxide...

Remote but not Distant: a Review on Experimental Models and Clinical Trials in Remote Ischemic Conditioning as Potential Therapy in Ischemic Stroke.

Molecular neurobiology

Mollet I, Marto JP, Mendonça M, Baptista MV, Vieira HLA.
PMID: 34686988
Mol Neurobiol. 2021 Oct 22; doi: 10.1007/s12035-021-02585-6. Epub 2021 Oct 22.

Stroke is one of the main causes of neurological disability worldwide and the second cause of death in people over 65 years old, resulting in great economic and social burden. Ischemic stroke accounts for 85% of total cases, and...

Low Doses of Resveratrol Protect Human Granulosa Cells from Induced-Oxidative Stress.

Antioxidants (Basel, Switzerland)

Moreira-Pinto B, Costa L, Felgueira E, Fonseca BM, Rebelo I.
PMID: 33916585
Antioxidants (Basel). 2021 Apr 04;10(4). doi: 10.3390/antiox10040561.

Resveratrol is a phytoalexin present in plant-derived foods, including grape's skin, cocoa, and peanuts. Evidence suggests that it has beneficial effects on human health because of its antioxidant properties. However, there is limited knowledge about the part played by...

Gene Therapy in Cancer Treatment: Why Go Nano?.

Pharmaceutics

Roma-Rodrigues C, Rivas-García L, Baptista PV, Fernandes AR.
PMID: 32151052
Pharmaceutics. 2020 Mar 05;12(3). doi: 10.3390/pharmaceutics12030233.

The proposal of gene therapy to tackle cancer development has been instrumental for the development of novel approaches and strategies to fight this disease, but the efficacy of the proposed strategies has still fallen short of delivering the full...

Feeding strategies to optimize vanillin production by Amycolatopsis sp. ATCC 39116.

Bioprocess and biosystems engineering

Valério R, Bernardino ARS, Torres CAV, Brazinha C, Tavares ML, Crespo JG, Reis MAM.
PMID: 33389106
Bioprocess Biosyst Eng. 2021 Apr;44(4):737-747. doi: 10.1007/s00449-020-02482-7. Epub 2021 Jan 02.

The growing consumer demand for natural products led to an increasing interest in vanillin production by biotechnological routes. In this work, the biotechnological vanillin production by Amycolatopsis sp. ATCC 39116 is studied using ferulic acid as precursor, aiming to...

Showing 1 to 5 of 5 entries