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Showing 1 to 12 of 21 entries
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PET Imaging of Angiogenesis.

PET clinics

Niu G, Chen X.
PMID: 20046926
PET Clin. 2009 Jan 01;4(1):17-38. doi: 10.1016/j.cpet.2009.04.011.

Angiogenesis is a highly-controlled process that is dependent on the intricate balance of both promoting and inhibiting factors, involved in various physiological and pathological processes. A comprehensive understanding of the molecular mechanisms that regulate angiogenesis has resulted in the...

Microfabricated magnetic sifter for high-throughput and high-gradient magnetic separation.

Journal of magnetism and magnetic materials

Earhart CM, Wilson RJ, White RL, Pourmand N, Wang SX.
PMID: 20161248
J Magn Magn Mater. 2009 May;321(10):1436-1439. doi: 10.1016/j.jmmm.2009.02.062.

A microfabricated magnetic sifter has been designed and fabricated for applications in biological sample preparation. The device enables high-throughput, high-gradient magnetic separation of magnetic nanoparticles by utilizing columnar fluid flow through a dense array (~5000/mm(2)) of micropatterned slots in...

Giant Magnetoresistive Sensors for DNA Microarray.

IEEE transactions on magnetics

Xu L, Yu H, Han SJ, Osterfeld S, White RL, Pourmand N, Wang SX.
PMID: 20824116
IEEE Trans Magn. 2008 Nov 01;44(11):3989-3991. doi: 10.1109/TMAG.2008.2002795.

Giant magnetoresistive (GMR) sensors are developed for a DNA microarray. Compared with the conventional fluorescent sensors, GMR sensors are cheaper, more sensitive, can generate fully electronic signals, and can be easily integrated with electronics and microfluidics. The GMR sensor...

Synthesis and characterization of PVP-coated large core iron oxide nanoparticles as an MRI contrast agent.

Nanotechnology

Lee HY, Lee SH, Xu C, Xie J, Lee JH, Wu B, Koh AL, Wang X, Sinclair R, Wang SX, Nishimura DG, Biswal S, Sun S, Cho SH, Chen X.
PMID: 21394237
Nanotechnology. 2008 Apr;19(16):165101. doi: 10.1088/0957-4484/19/16/165101.

The purpose of this study was to synthesize biocompatible polyvinylpyrrolidone (PVP)-coated iron oxide (PVP-IO) nanoparticles and to evaluate their efficacy as a magnetic resonance imaging (MRI) contrast agent. The PVP-IO nanoparticles were synthesized by a thermal decomposition method and...

Silane-based functionalization of synthetic antiferromagnetic nanoparticles for biomedical applications.

Journal of applied physics

Zhang M, Hu W, Earhart CM, Tang M, Wilson RJ, Wang SX.
PMID: 20552036
J Appl Phys. 2010 May 01;107(9):9B325. doi: 10.1063/1.3355906. Epub 2010 May 14.

Synthetic antiferromagnetic nanoparticles (SAFNPs) have been successfully coated with two different kinds of silanes, 3-aminopropyltrimethoxysilane and 2-[methoxy(polyethyleneoxy)propyl]trimethoxysilane. The morphology of SAF particles is characterized by scanning electron microscopy and magnetic properties by alternating gradient magnetometry. The attachment of silane...

In situ study of the impact of inter- and intra-reader variability on region of interest (ROI) analysis in preclinical molecular imaging.

American journal of nuclear medicine and molecular imaging

Habte F, Budhiraja S, Keren S, Doyle TC, Levin CS, Paik DS.
PMID: 23526701
Am J Nucl Med Mol Imaging. 2013;3(2):175-81. Epub 2013 Mar 08.

We estimated reader-dependent variability of region of interest (ROI) analysis and evaluated its impact on preclinical quantitative molecular imaging. To estimate reader variability, we used five independent image datasets acquired each using microPET and multispectral fluorescence imaging (MSFI). We...

Live imaging of follicle stimulating hormone receptors in gonads and bones using near infrared II fluorophore.

Chemical science

Feng Y, Zhu S, Antaris AL, Chen H, Xiao Y, Lu X, Jiang L, Diao S, Yu K, Wang Y, Herraiz S, Yue J, Hong X, Hong G, Cheng Z, Dai H, Hsueh AJ.
PMID: 28626555
Chem Sci. 2017 May 01;8(5):3703-3711. doi: 10.1039/c6sc04897h. Epub 2017 Mar 06.

No abstract available.

Synthetic antiferromagnetic nanoparticles with tunable susceptibilities.

Journal of applied physics

Hu W, Wilson RJ, Earhart CM, Koh AL, Sinclair R, Wang SX.
PMID: 19529797
J Appl Phys. 2009 Apr 01;105(7):7B508. doi: 10.1063/1.3072028. Epub 2009 Feb 06.

High-moment monodisperse disk-shaped Co-Fe magnetic nanoparticles, stable in aqueous solution, were physically fabricated by using nanoimprinted templates and vacuum deposition techniques. These multilayer synthetic antiferromagnetic nanoparticles exhibit nearly zero magnetic remanence and coercivity, and susceptibilities which can be tuned...

High-resolution, serial intravital microscopic imaging of nanoparticle delivery and targeting in a small animal tumor model.

Nano today

Smith BR, Zavaleta C, Rosenberg J, Tong R, Ramunas J, Liu Z, Dai H, Gambhir SS.
PMID: 24273594
Nano Today. 2013 Apr;8(2). doi: 10.1016/j.nantod.2013.02.004.

Nanoparticles are under active investigation for the detection and treatment of cancer. Yet our understanding of nanoparticle delivery to tumors is limited by our ability to observe the uptake process on its own scale in living subjects. We chose...

Wafer-scale synthesis of monodisperse synthetic magnetic multilayer nanorods.

Nano letters

Zhang M, Bechstein DJ, Wilson RJ, Wang SX.
PMID: 24329003
Nano Lett. 2014 Jan 08;14(1):333-8. doi: 10.1021/nl404089t. Epub 2013 Dec 17.

A double exposure technique has been used to fabricate nanoimprint stamps for making monodisperse nanorods with controllable lengths. The nanorod length is defined by a normal photolithography projection process whereas the nanorod width is defined by an edge-lithography process...

A 256 pixel magnetoresistive biosensor microarray in 0.18μm CMOS.

IEEE journal of solid-state circuits

Hall DA, Gaster RS, Makinwa K, Wang SX, Murmann B.
PMID: 24761029
IEEE J Solid-State Circuits. 2013 May;48(5):1290-1301. doi: 10.1109/JSSC.2013.2245058.

Magnetic nanotechnologies have shown significant potential in several areas of nanomedicine such as imaging, therapeutics, and early disease detection. Giant magnetoresistive spin-valve (GMR SV) sensors coupled with magnetic nanotags (MNTs) possess great promise as ultra-sensitive biosensors for diagnostics. We...

InAs/InP/ZnSe Core/Shell/Shell Quantum Dots as Near-Infrared Emitters: Bright, Narrow-Band, Non-Cadmium Containing, and Biocompatible.

Nano research

Xie R, Chen K, Chen X, Peng X.
PMID: 20631914
Nano Res. 2008 Dec 14;1(6):457-464. doi: 10.1007/s12274-008-8048-x.

High quality InAs/InP/ZnSe core/shell/shell quantum dots have been grown by a one-pot approach. This engineered quantum dots with unique near-infrared (NIR) fluorescence, possessing outstanding optical properties, and the biocompatibility desired for in vivo applications. The resulting quantum dots have...

Showing 1 to 12 of 21 entries