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Showing 1 to 12 of 2936 entries
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[Use of antistaphylococcal plasma in the complex therapy of staphylococcal sepsis in premature children].

Pediatriia

Tabolin VA, Skurkovich SV, Ionova IA, Papko GF, Molotkova LS, Ermolaeva VA.
PMID: 5497977
Pediatriia. 1970 Oct;49(10):27-30.

No abstract available.

A selective histone deacetylase-6 inhibitor improves BDNF trafficking in hippocampal neurons from Mecp2 knockout mice: implications for Rett syndrome.

Frontiers in cellular neuroscience

Xu X, Kozikowski AP, Pozzo-Miller L.
PMID: 24639629
Front Cell Neurosci. 2014 Mar 07;8:68. doi: 10.3389/fncel.2014.00068. eCollection 2014.

Rett syndrome (RTT) is a neurodevelopmental disorder caused by loss-of-function mutations in the transcriptional modulator methyl-CpG-binding protein 2 (MECP2). One of the most prominent gene targets of MeCP2 is brain-derived neurotrophic factor (Bdnf), a potent modulator of activity-dependent synaptic...

Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons.

Nature communications

Weinert T, Olieric N, Cheng R, Brünle S, James D, Ozerov D, Gashi D, Vera L, Marsh M, Jaeger K, Dworkowski F, Panepucci E, Basu S, Skopintsev P, Doré AS, Geng T, Cooke RM, Liang M, Prota AE, Panneels V, Nogly P, Ermler U, Schertler G, Hennig M, Steinmetz MO, Wang M, Standfuss J.
PMID: 28912485
Nat Commun. 2017 Sep 14;8(1):542. doi: 10.1038/s41467-017-00630-4.

Historically, room-temperature structure determination was succeeded by cryo-crystallography to mitigate radiation damage. Here, we demonstrate that serial millisecond crystallography at a synchrotron beamline equipped with high-viscosity injector and high frame-rate detector allows typical crystallographic experiments to be performed at...

Albendazole induces oxidative stress and DNA damage in the parasitic protozoan Giardia duodenalis.

Frontiers in microbiology

Martínez-Espinosa R, Argüello-García R, Saavedra E, Ortega-Pierres G.
PMID: 26300866
Front Microbiol. 2015 Aug 06;6:800. doi: 10.3389/fmicb.2015.00800. eCollection 2015.

The control of Giardia duodenalis infections is carried out mainly by drugs, among these albendazole (ABZ) is commonly used. Although the cytotoxic effect of ABZ usually involves binding to β-tubulin, it has been suggested that oxidative stress may also...

Evidence that phospholipase C is involved in the antitumour action of NSC768313, a new thieno[2,3-b]pyridine derivative.

Cancer cell international

Reynisson J, Jaiswal JK, Barker D, D'mello SA, Denny WA, Baguley BC, Leung EY.
PMID: 26966420
Cancer Cell Int. 2016 Mar 10;16:18. doi: 10.1186/s12935-016-0293-6. eCollection 2016.

BACKGROUND: The thieno[2,3-b]pyridines were discovered by virtual high throughput screening as potential inhibitors of phospholipase C (PLC) isoforms and showed potent growth inhibitory effects in National Cancer Institute's human tumour cell line panel (NCI60). The mechanism of the anti-proliferative...

Comparative localization of serotonin-like immunoreactive cells in Thaliacea informs tunicate phylogeny.

Frontiers in zoology

Valero-Gracia A, Marino R, Crocetta F, Nittoli V, Tiozzo S, Sordino P.
PMID: 27708681
Front Zool. 2016 Sep 29;13:45. doi: 10.1186/s12983-016-0177-6. eCollection 2016.

BACKGROUND: Thaliaceans is one of the understudied classes of the phylum Tunicata. In particular, their phylogenetic relationships remain an issue of debate. The overall pattern of serotonin (5-HT) distribution is an excellent biochemical trait to interpret internal relationships at...

Canova medication changes TNF-α and IL-10 serum levels in mice infected with Trypanosoma cruzi Y strain.

Asian Pacific journal of tropical medicine

Pupulin ÁRT, Bracht L, de Oliveira Dalalio MM, de Souza Silva-Comar FM, da Rocha BA, Ames FQ, Cuman RKN, Bersani-Amado CA.
PMID: 27633299
Asian Pac J Trop Med. 2016 Sep;9(9):860-865. doi: 10.1016/j.apjtm.2016.07.007. Epub 2016 Jul 26.

OBJECTIVE: To identify whether Canova medication changes TNF-α and IL-10 serum levels in mice infected with Trypanosoma cruzi Y strain.METHODS: Animals were divided into five groups: non-treated infected animals (I); benznidazole-treated infected animals (Bz; 100 mg/kg body weight, single...

Study of Cell Division Aberrations Induced by Some Silica Dusts in Mammalian Cells in Vitro.

Inhalation toxicology

Béna F, Danière MC, Terzetti F, Poirot O, Elias Z.
PMID: 26368616
Inhal Toxicol. 2000 Jan;12:189-98. doi: 10.1080/08958378.2000.11463213.

Previously we observed that some crystalline and amorphous (diatomaceous earths) silicas (but not pyrogenic amorphous silica) induced morphological transformation of Syrian hamster embryo (SHE) cells. In order to explore the mechanisms of the silica-induced cell transformation, in this study...

Influenzanet: Citizens Among 10 Countries Collaborating to Monitor Influenza in Europe.

JMIR public health and surveillance

Koppeschaar CE, Colizza V, Guerrisi C, Turbelin C, Duggan J, Edmunds WJ, Kjelsø C, Mexia R, Moreno Y, Meloni S, Paolotti D, Perrotta D, van Straten E, Franco AO.
PMID: 28928112
JMIR Public Health Surveill. 2017 Sep 19;3(3):e66. doi: 10.2196/publichealth.7429.

BACKGROUND: The wide availability of the Internet and the growth of digital communication technologies have become an important tool for epidemiological studies and health surveillance. Influenzanet is a participatory surveillance system monitoring the incidence of influenza-like illness (ILI) in...

Long nonding RNA UCA1 regulates neural stem cell differentiation by controlling miR-1/Hes1 expression.

American journal of translational research

Zheng J, Yi D, Liu Y, Wang M, Zhu Y, Shi H.
PMID: 28861160
Am J Transl Res. 2017 Aug 15;9(8):3696-3704. eCollection 2017.

Neural stem cells are able to self-renew and generate glial and neuronal lineages. Neural stem cell may serve as therapeutic method for neurological disorders including spinal cord injuries, Parkinson's disease, Huntington's disease and Alzheimer's disease. Long noncoding RNAs (lncRNAs)...

Expression of tubulin folding cofactor B in mouse hepatic ischemia-reperfusion injury.

Biomedical reports

Gong J, Wang J, Tian Y, Zhang J, Liang W, Li Z, Yu J, Tang B, He S.
PMID: 28515911
Biomed Rep. 2017 May;6(5):525-531. doi: 10.3892/br.2017.891. Epub 2017 Apr 11.

The aim of the present study was to investigate the association between tubulin folding cofactor B (TBCB) expression and ischemia-reperfusion injury (IRI) in mice. A total of 48 C57BL/6 mice were randomly divided into a control group (Sham, n=6)...

Comparison of LabSOCS and GESPECOR codes used in gamma-ray spectrometry.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine

Done L, Tugulan LC, Gurau D, Dragolici F, Alexandru C.
PMID: 26625727
Appl Radiat Isot. 2016 Mar;109:539-543. doi: 10.1016/j.apradiso.2015.11.036. Epub 2015 Nov 21.

Two dedicated software packages -LabSOCS and GESPECOR- for efficiency evaluation in gamma-ray spectrometry, were compared for equivalence. The detection efficiency and the coincidence-summing corrections coefficients were calculated for a specific HPGe detector, for different sample parameters and energies typically...

Showing 1 to 12 of 2936 entries