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Showing 1 to 12 of 44 entries
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Apolipoprotein M.

Lipids in health and disease

Luo G, Zhang X, Nilsson-Ehle P, Xu N.
PMID: 15461812
Lipids Health Dis. 2004 Oct 04;3:21. doi: 10.1186/1476-511X-3-21.

Apolipoprotein M (apoM) is a 26-kDa protein that is mainly associated with high-density lipoprotein (HDL) in human plasma, with a small proportion present in triglyceride-rich lipoproteins (TGRLP) and low-density lipoproteins (LDL). Human apoM gene is located in p21.31 on...

Organotypic and epidermal-dermal co-cultures of normal human keratinocytes and dermal cells: Regulation of transforming growth factor alpha, beta1 and beta2 mRNA levels.

Toxicology in vitro : an international journal published in association with BIBRA

Smola H, Thiekötter G, Baur M, Stark HJ, Breitkreutz D, Fusenig NE.
PMID: 20692978
Toxicol In Vitro. 1994 Aug;8(4):641-50. doi: 10.1016/0887-2333(94)90034-5.

Epidermal-dermal cell-cell interactions are recognized to influence keratinocyte proliferation in vivo as well as in vitro. To study the underlying molecular mechanisms of epithelial-mesenchymal interactions epidermal-dermal cell co-cultures and organotypic cultures were used. Steady-state mRNA levels are described for...

Does single intramuscular application of autologous conditioned plasma influence systemic circulating growth factors?.

Journal of sports science & medicine

Schippinger G, Fankhauser F, Oettl K, Spirk S, Hofmann P.
PMID: 24149367
J Sports Sci Med. 2012 Sep 01;11(3):551-6. eCollection 2012.

Platelet-rich plasma (PRP) has been employed to treat sports injuries to possibly accelerate healing and regeneration. This method offers some potential, especially for athletes. Growth factors are generally prohibited by the World Anti Doping Agency with exception to PRP...

Extraction Socket Preservation Using Growth Factors and Stem Cells: a Systematic Review.

Journal of oral & maxillofacial research

Pranskunas M, Galindo-Moreno P, Padial-Molina M.
PMID: 31620269
J Oral Maxillofac Res. 2019 Sep 05;10(3):e7. doi: 10.5037/jomr.2019.10307. eCollection 2019.

OBJECTIVES: To evaluate the reported literature on the use of stem cells or growth factors for post extraction treatment of the alveolar bone.MATERIAL AND METHODS: A NCBI PubMed and PubMed Central databases search was conducted between September 2010 and...

Genetic and .

Human fertility (Cambridge, England)

Matheus Bremm J, Michels M, Duarte Rengel B, Gomes FG, Fraga LR, Sanseverino MTV.
PMID: 34030553
Hum Fertil (Camb). 2021 May 25;1-10. doi: 10.1080/14647273.2021.1922764. Epub 2021 May 25.

Recurrent pregnancy loss (RPL) is one of the most common reproductive failures affecting 1-5% of couples. Smad3 is an effector of signalling of the Transforming Growth Factors-β superfamily (TGF-β), regulating the transcription of several target genes of these cytokines....

If ineffective levels of transforming growth factors and their receptor account for old age being a risk factor for Alzheimer's disease, then increasing TGFBR2 might be therapeutic.

Alzheimer's & dementia (New York, N. Y.)

Fessel J.
PMID: 32382652
Alzheimers Dement (N Y). 2020 May 06;6(1):e12019. doi: 10.1002/trc2.12019. eCollection 2020.

If it is correct that ineffective levels of transforming growth factors beta and their receptor account for old age being a risk factor for Alzheimer's disease (AD), then increasing TGFBR2 might be therapeutic. Pacltaxel is a direct way to...

Silencing Histone Deacetylase 7 Alleviates Transforming Growth Factor-β1-Induced Profibrotic Responses in Fibroblasts Derived from Peyronie's Plaque.

The world journal of men's health

Kang DH, Yin GN, Choi MJ, Song KM, Ghatak K, Minh NN, Kwon MH, Seong DH, Ryu JK, Suh JK.
PMID: 29706035
World J Mens Health. 2018 May;36(2):139-146. doi: 10.5534/wjmh.170005.

PURPOSE: Epigenetic modifications, such as histone acetylation/deacetylation and DNA methylation, play a crucial role in the pathogenesis of inflammatory disorders and fibrotic diseases. The aim of this study was to study the differential gene expression of histone deacetylases (HDACs)...

Residues of Alpha Helix H3 Determine Distinctive Features of Transforming Growth Factor β3.

The journal of physical chemistry. B

Nayeem SM, Oteri F, Baaden M, Deep S.
PMID: 28497965
J Phys Chem B. 2017 Jun 08;121(22):5483-5498. doi: 10.1021/acs.jpcb.7b01867. Epub 2017 May 24.

Transforming growth factors (TGF-βs) are proteins that regulate cell growth by binding to their receptors. In contrast to transforming growth factor (TGF) β1, TGF-β3 homodimer is believed to exist also in an open conformation, in which both of its...

Vascular endothelial growth factor.

Trends in cardiovascular medicine

Ferrara N.
PMID: 21244915
Trends Cardiovasc Med. 1993 Nov-Dec;3(6):244-50. doi: 10.1016/1050-1738(93)90046-9.

An understanding of the mechanisms regulating growth and differentiation of vascular endothelial cells is very important for cardiovascular biology and medicine. Several potential regulators of angiogenesis have been identified, including acidic and basic fibroblast growth factors, epidermal growth factor,...

Transforming growth-factor-alpha and factor-beta(1) levels in plasma and effusions from patients with cancer or hematologic malignancies.

International journal of oncology

Witters L, Almondhiry H, Matthews Y, Walker R, Langton B, Dasch J, Lipton A.
PMID: 21567004
Int J Oncol. 1994 Apr;4(4):943-50. doi: 10.3892/ijo.4.4.943.

Transforming growth factors-alpha and -beta1 are thought to play a role in carcinogenesis. Using a sandwich linked immunosorbent assay, we have measured TGF-alpha and -beta1 levels in malignant human plasma and effusions. TGF-alpha and -beta1 plasma levels were not...

Bone morphogenetic protein signaling: implications in urology.

Korean journal of urology

Jeong J, Kang DI, Lee GT, Kim IY.
PMID: 20733955
Korean J Urol. 2010 Aug;51(8):511-7. doi: 10.4111/kju.2010.51.8.511. Epub 2010 Aug 18.

The bone morphogenetic proteins (BMPs), as members of the transforming growth factor-beta (TGF-beta) superfamily, not only control bone formation, but also regulate multiple key steps during embryonic development and differentiation. Furthermore, BMPs play critical roles in maintaining the homeostasis...

Expression of epidermal and transforming growth factors in pancreatic cancer.

Oncology reports

Lakshmikesari A, Radhakrishna R, Bhanumathi A, Ravi D, Srinivas G, Nair M, Pillai M.
PMID: 21594491
Oncol Rep. 1996 Sep;3(5):963-6. doi: 10.3892/or.3.5.963.

Pancreatic cancer continues to be a major clinical problem and little is known of the various cellular and molecular events associated with this malignancy. Growth factors and their receptors have important functions in the process of tumor progression. We...

Showing 1 to 12 of 44 entries