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Showing 1 to 12 of 511 entries
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Enzymatic Methylation of Arsenic Compounds.

Toxicology and applied pharmacology

Zakharyan RA, Wildfang E, Aposhian HV.
PMID: 8813004
Toxicol Appl Pharmacol. 1996 Sep;140(1):77-84.

The methylation of inorganic arsenic to monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA) have been generally considered to be the major pathway for inorganic arsenic biotransformation and detoxification. Yet, when arsenate/arsenite is injected into the Callithrix jacchus (marmoset) monkey...

In Ovo 2,3,7,8-Tetrachlorodibenzo-p-dioxin Exposure in Three Avian Species.

Toxicology and applied pharmacology

Janz DM, Bellward GD.
PMID: 8813006
Toxicol Appl Pharmacol. 1996 Aug;139(2):292-300.

As opposed to mammals, the heterogametic sex in birds is female, and sexual differentiation of the central nervous system away from the intrinsic male pattern is dependent on ovarian estrogen secretions during the perinatal period. The contamination of aquatic...

Chemical index for volume 163.

Toxicology and applied pharmacology

[No authors listed]
PMID: 10702368
Toxicol Appl Pharmacol. 2000 Mar 15;163(3):294-5. doi: 10.1006/taap.2000.8916.

No abstract available.

Clinton H. Thienes (August 9, 1896-May 18, 1976).

Toxicology and applied pharmacology

Haley TJ.
PMID: 320717
Toxicol Appl Pharmacol. 1977 Jan;39(1):153-4. doi: 10.1016/0041-008x(77)90188-0.

No abstract available.

Arsenic trioxide-induced p38 MAPK and Akt mediated MCL1 downregulation causes apoptosis of BCR-ABL1-positive leukemia cells.

Toxicology and applied pharmacology

Huang CH, Lee YC, Chiou JT, Shi YJ, Wang LJ, Chang LS.
PMID: 32305283
Toxicol Appl Pharmacol. 2020 Apr 17;397:115013. doi: 10.1016/j.taap.2020.115013. Epub 2020 Apr 17.

In this study, we investigated the mechanisms underlying arsenic trioxide (ATO)-induced death of human BCR-ABL1-positive K562 and MEG-01 cells. ATO-induced apoptotic death in K562 cells was characterized by ROS-mediated mitochondrial depolarization, MCL1 downregulation, p38 MAPK activation, and Akt inactivation....

Mechanism underlying hooked resurgent-like tail currents induced by an insecticide in human cardiac Nav1.5.

Toxicology and applied pharmacology

Thull S, Neacsu C, O'Reilly AO, Bothe S, Hausmann R, Huth T, Meents J, Lampert A.
PMID: 32302602
Toxicol Appl Pharmacol. 2020 Apr 15;397:115010. doi: 10.1016/j.taap.2020.115010. Epub 2020 Apr 15.

Voltage-gated sodium channels are responsible not only for the fast upstroke of the action potential, but they also modify cellular excitability via persistent and resurgent currents. Insecticides act via permanently opening sodium channels to immobilize the animals. Cellular recordings...

Corrigendum.

Toxicology and applied pharmacology

[No authors listed]
PMID: 20852735
Toxicol Appl Pharmacol. 2010 Jun 01;245(2):280. doi: 10.1016/j.taap.2010.03.018.

No abstract available.

Cumulative subject index for volumes 148-153 .

Toxicology and applied pharmacology

[No authors listed]
PMID: 9878597
Toxicol Appl Pharmacol. 1998 Dec;153(2):267-90. doi: 10.1006/taap.1998.8604.

No abstract available.

Cumulative chemical index for volumes 148-153 .

Toxicology and applied pharmacology

[No authors listed]
PMID: 9878598
Toxicol Appl Pharmacol. 1998 Dec;153(2):291-3. doi: 10.1006/taap.1998.8605.

No abstract available.

Chemical Index for Volume 152.

Toxicology and applied pharmacology

[No authors listed]
PMID: 9878584
Toxicol Appl Pharmacol. 1998 Oct;152(2):422. doi: 10.1006/taap.1998.8571.

No abstract available.

Chemical index for volume 156 .

Toxicology and applied pharmacology

[No authors listed]
PMID: 10222317
Toxicol Appl Pharmacol. 1999 May 01;156(3):247. doi: 10.1006/taap.1999.8678.

No abstract available.

Evaluation of β-adrenergic ligands for development of pharmacological heart failure and transparency models in zebrafish.

Toxicology and applied pharmacology

Maciag M, Wnorowski A, Bednarz K, Plazinska A.
PMID: 34838787
Toxicol Appl Pharmacol. 2021 Nov 26;434:115812. doi: 10.1016/j.taap.2021.115812. Epub 2021 Nov 26.

Cardiovascular toxicity represents one of the most common reasons for clinical trial failure. Consequently, early identification of novel cardioprotective strategies could prevent the later-stage drug-induced cardiac side effects. The use of zebrafish (Danio rerio) in preclinical studies has greatly...

Showing 1 to 12 of 511 entries