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Showing 1 to 7 of 7 entries
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Reaction Coordinate-Free Approach to Recovering Kinetics from Potential-Scaled Simulations: Application of Kramers' Rate Theory.

The journal of physical chemistry. B

Frank AT, Andricioaei I.
PMID: 27220565
J Phys Chem B. 2016 Aug 25;120(33):8600-5. doi: 10.1021/acs.jpcb.6b02654. Epub 2016 Jun 06.

Enhanced sampling techniques are used to increase the frequency of "rare events" during computer simulations of complex molecules. Although methods exist that allow accurate thermodynamics to be recovered from enhanced simulations, recovering kinetics proves to be more challenging. Here...

The Role of CD44 in Disease Pathophysiology and Targeted Treatment.

Frontiers in immunology

Jordan AR, Racine RR, Hennig MJ, Lokeshwar VB.
PMID: 25954275
Front Immunol. 2015 Apr 21;6:182. doi: 10.3389/fimmu.2015.00182. eCollection 2015.

The cell-surface glycoprotein CD44 is involved in a multitude of important physiological functions including cell proliferation, adhesion, migration, hematopoiesis, and lymphocyte activation. The diverse physiological activity of CD44 is manifested in the pathology of a number of diseases including...

The AGE-RAGE Axis: Implications for Age-Associated Arterial Diseases.

Frontiers in genetics

Senatus LM, Schmidt AM.
PMID: 29259621
Front Genet. 2017 Dec 05;8:187. doi: 10.3389/fgene.2017.00187. eCollection 2017.

The process of advanced glycation leads to the generation and accumulation of an heterogeneous class of molecules called advanced glycation endproducts, or AGEs. AGEs are produced to accelerated degrees in disorders such as diabetes, renal failure, inflammation, neurodegeneration, and...

Use of Caenorhabditis elegans as a model to study Alzheimer's disease and other neurodegenerative diseases.

Frontiers in genetics

Alexander AG, Marfil V, Li C.
PMID: 25250042
Front Genet. 2014 Sep 05;5:279. doi: 10.3389/fgene.2014.00279. eCollection 2014.

Advances in research and technology has increased our quality of life, allowed us to combat diseases, and achieve increased longevity. Unfortunately, increased longevity is accompanied by a rise in the incidences of age-related diseases such as Alzheimer's disease (AD)....

Depth-resolved imaging of colon tumor using optical coherence tomography and fluorescence laminar optical tomography.

Biomedical optics express

Tang Q, Wang J, Frank A, Lin J, Li Z, Chen CW, Jin L, Wu T, Greenwald BD, Mashimo H, Chen Y.
PMID: 28018738
Biomed Opt Express. 2016 Nov 21;7(12):5218-5232. doi: 10.1364/BOE.7.005218. eCollection 2016 Dec 01.

Early detection of neoplastic changes remains a critical challenge in clinical cancer diagnosis and treatment. Many cancers arise from epithelial layers such as those of the gastrointestinal (GI) tract. Current standard endoscopic technology is difficult to detect the subsurface...

Social Support Buffers the Impact of Depressive Symptoms on Life Satisfaction in Old Age.

Clinical gerontologist

Adams TR, Rabin LA, Da Silva VG, Katz MJ, Fogel J, Lipton RB.
PMID: 27418714
Clin Gerontol. 2016;39(2):139-157. doi: 10.1080/07317115.2015.1073823. Epub 2015 Aug 07.

OBJECTIVES: Life satisfaction is an important component of overall well-being. Decline in life satisfaction is related to many adverse health outcomes including mortality.METHODS: We investigate the association of various psychosocial and health-related factors to life satisfaction in 237 non-demented...

Hydrogenation of quinoline by ruthenium nanoparticles immobilized on poly(4-vinylpyridine).

Catalysis communications

Sánchez-Delgado RA, Machalaba N, Ng-A-Qui N.
PMID: 19050746
Catal Commun. 2007 Dec;8(12):2115-2118. doi: 10.1016/j.catcom.2007.04.006.

A series of catalysts composed of ruthenium nanoparticles immobilized on poly(4-vinylpyridine) was prepared by NaBH(4) reduction of RuCl(3).3H(2)O in methanol in the presence of the polymer; TEM measurements of a 10 wt % Ru/P4VPy material indicate that ruthenium particles...

Showing 1 to 7 of 7 entries