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Diversification of biogenic amines, substance P and neurotrophic factor produces chronic muscular pain and tactile allodynia accompanied by depression--A putative …

STEM and diversification

Arora V.
GSID: X6YFPAbT4RIJ
V Arora, A Kuhad, K Chopra - The Journal of Pain, 2012 - jpain.org

Numerous studies point to the frequent co-morbidity between pain and depression. In clinical practice, depression is often associated with an increased incidence of clinical pain complaints and thus, the co-morbidity of pain and depression has been suggested to be...

Omentum Free Flap Anastomosed to Arterial Bypass in Open Knee Dislocation: Case Report and Discussion.

Eplasty

Pauchot J, Ducroux E, Leclerc G, Obert L, Sergent AP.
PMID: 26171093
Eplasty. 2015 Jun 11;15:e21. eCollection 2015.

OBJECTIVE: To report on the original surgical management of a patient with severe trauma of both legs involving anastomosis of an omentum free flap with an emergency vascular bypass.METHODS: After stabilization of the knee with an external fixator, a...

Targeting NK-1 Receptors to Prevent and Treat Pancreatic Cancer: a New Therapeutic Approach.

Cancers

Muñoz M, Coveñas R.
PMID: 26154566
Cancers (Basel). 2015 Jul 06;7(3):1215-32. doi: 10.3390/cancers7030832.

Pancreatic cancer (PC) is the fourth leading cause of cancer related-deaths in both men and women, and the 1- and 5-year relative survival rates are 25% and 6%, respectively. It is known that smoking, alcoholism and psychological stress are...

Peptide Extracts from Cultures of Certain Lactobacilli Inhibit Helicobacter pylori.

Probiotics and antimicrobial proteins

De Vuyst L, Vincent P, Makras E, Leroy F, Pot B.
PMID: 26780898
Probiotics Antimicrob Proteins. 2010 Mar;2(1):26-36. doi: 10.1007/s12602-009-9029-4.

Helicobacter pylori inhibition by probiotic lactobacilli has been observed in vitro and in vivo. Carefully selected probiotic Lactobacillus strains could therefore play an important role in the treatment of H. pylori infection and eradication. However, the underlying mechanism for...

Resiniferatoxin for Pain Treatment: An Interventional Approach to Personalized Pain Medicine.

The open pain journal

Iadarola MJ, Gonnella GL.
PMID: 26779292
Open Pain J. 2013;6:95-107. doi: 10.2174/1876386301306010095. Epub 2013 Mar 08.

This review examines existing preclinical and clinical studies related to resiniferatoxin (RTX) and its potential uses in pain treatment. Like capsaicin, RTX is a vanilloid receptor (TRPV1) agonist, only more potent. This increased potency confers both quantitative and qualitative...

Nutmeg oil alleviates chronic inflammatory pain through inhibition of COX-2 expression and substance P release in vivo.

Food & nutrition research

Zhang WK, Tao SS, Li TT, Li YS, Li XJ, Tang HB, Cong RH, Ma FL, Wan CJ.
PMID: 27121041
Food Nutr Res. 2016 Apr 26;60:30849. doi: 10.3402/fnr.v60.30849. eCollection 2016.

BACKGROUND: Chronic pain, or sometimes referred to as persistent pain, reduces the life quality of patients who are suffering from chronic diseases such as inflammatory diseases, cancer and diabetes. Hence, herbal medicines draw many attentions and have been shown...

Gastric emptying and plasma levels of gastrointestinal hormones in patients with peptic ulcer.

World journal of gastroenterology

Chen J, Li JM, Li XH, Hao HS, Fu SH.
PMID: 27053894
World J Gastroenterol. 1997 Dec 15;3(4):270. doi: 10.3748/wjg.v3.i4.270.

AIM: To study the plasma level of gastrointestinal hormones and the time of gastric emptying in patients with peptic ulcer.METHODS: Thirty patients with gastric ulcer (GU), 29 patients with duodenal ulcer (DU), and 12 healthy controls were studied. Plasma...

Central mediators involved in the febrile response: effects of antipyretic drugs.

Temperature (Austin, Tex.)

Zampronio AR, Soares DM, Souza GE.
PMID: 27227071
Temperature (Austin). 2015 Oct 13;2(4):506-21. doi: 10.1080/23328940.2015.1102802. eCollection 2015.

Fever is a complex signal of inflammatory and infectious diseases. It is generally initiated when peripherally produced endogenous pyrogens reach areas that surround the hypothalamus. These peripheral endogenous pyrogens are cytokines that are produced by leukocytes and other cells,...

The role of substance p in ischaemic brain injury.

Brain sciences

Turner RJ, Vink R.
PMID: 24961310
Brain Sci. 2013 Jan 30;3(1):123-42. doi: 10.3390/brainsci3010123.

Stroke is a leading cause of death, disability and dementia worldwide. Despite extensive pre-clinical investigation, few therapeutic treatment options are available to patients, meaning that death, severe disability and the requirement for long-term rehabilitation are common outcomes. Cell loss...

Measurement of substance P and met-enkephalin in the serum of violent death victims.

Forensic science, medicine, and pathology

Quarino L, Shaler RC.
PMID: 25868768
Forensic Sci Med Pathol. 2006 Dec;2(4):231-9. doi: 10.1385/FSMP:2:4:231.

Very often the allocation of putative damages for wrongful death and the determination of aggravating factors in the sentencing of an individual convicted of homicide by a jury is based on a subjective determination of the amount of pain...

Effects of acupuncture knife on inflammatory factors and pain in third lumbar vertebrae transverse process syndrome model rats.

Evidence-based complementary and alternative medicine : eCAM

Yu JN, Guo CQ, Hu B, Liu NG, Sun HM, Xu H, Wu HX, Guo Y, Liang CX, Chen ZX, Li XH.
PMID: 25544854
Evid Based Complement Alternat Med. 2014;2014:892406. doi: 10.1155/2014/892406. Epub 2014 Dec 02.

The aim of this paper was to explore the long-term effects and pain relief mechanism of acupuncture knife on third lumbar vertebrae (L3) transverse process syndrome. Forty SD rats were randomized into control, model, electroacupuncture (EA), and acupuncture knife...

NK1-receptor-expressing paraventricular nucleus neurones modulate daily variation in heart rate and stress-induced changes in heart rate variability.

Physiological reports

Feetham CH, Barrett-Jolley R.
PMID: 25472606
Physiol Rep. 2014 Dec 03;2(12). doi: 10.14814/phy2.12207. Print 2014 Dec 01.

The paraventricular nucleus of the hypothalamus (PVN) is an established center of cardiovascular control, receiving projections from other nuclei of the hypothalamus such as the dorsomedial hypothalamus and the suprachiasmatic nucleus. The PVN contains a population of "pre-autonomic neurones"...

Showing 1 to 12 of 963 entries